65 citations,
June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
57 citations,
September 2017 in “Journal of controlled release” Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
55 citations,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
53 citations,
November 1992 in “Mayo Clinic Proceedings” HIV can cause unusual and severe skin problems that are hard to treat.
52 citations,
January 1999 in “Journal of Small Animal Practice” Removing a cat's pancreatic cancer can temporarily reverse hair loss caused by the disease.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
47 citations,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
43 citations,
February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
42 citations,
April 2012 in “Seminars in Oncology” Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
41 citations,
June 2006 in “Journal of Investigative Dermatology” Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
33 citations,
October 2010 in “Journal of Dermatological Science” Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
32 citations,
February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
31 citations,
May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
31 citations,
December 2010 in “International Journal of Andrology” Men with testicular cancer were less likely to experience baldness and severe acne.
30 citations,
September 2017 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
30 citations,
October 2014 in “PLOS ONE” BAF200 is essential for proper heart and coronary artery formation.
29 citations,
February 2016 in “Scandinavian journal of urology” Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
28 citations,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
26 citations,
May 2017 in “Lasers in Medical Science” Laser therapy and hair growth factors significantly improve hair density in male baldness.
25 citations,
March 2017 in “Steroids” Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
24 citations,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
24 citations,
January 2012 in “Journal of Cellular Biochemistry” C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
23 citations,
September 2015 in “International Journal of Molecular Medicine” Activating ER-β, not ER-α, improves skin cell growth and wound healing.
21 citations,
October 2018 in “European Journal of Pharmacology” Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
21 citations,
March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
20 citations,
August 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
19 citations,
June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
18 citations,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.