Dermatologic Manifestations of Human Immunodeficiency Virus Infection

    November 1992 in “ Mayo Clinic Proceedings ”
    Mark J. Zalla, W.P. Daniel Su, Anthony F. Fransway
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    TLDR HIV can cause unusual and severe skin problems that are hard to treat.
    The document from 1992 provides a comprehensive review of the dermatologic manifestations associated with HIV infection, emphasizing that skin conditions in HIV-positive patients are often atypical, more severe, and less responsive to treatment. It covers a wide range of skin disorders, including neoplastic processes like Kaposi's sarcoma, various infections by viruses such as HPV, herpes simplex, and varicella-zoster, bacterial infections like those caused by Staphylococcus aureus, and fungal infections such as candidiasis. The review also discusses mucocutaneous manifestations, including oral conditions, hair diseases like alopecia, and nail diseases. It highlights the importance of recognizing these conditions for proper diagnosis and management, noting that some manifestations, such as eosinophilic folliculitis, can serve as markers for the risk of opportunistic infections. The document underscores the need for increased awareness and appropriate therapy for these dermatologic signs in HIV-infected individuals.
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