10 citations
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December 2020 in “Dermatologic Therapy” This study found that topical minoxidil 5% gel and spironolactone 1% gel were both effective treatments for androgenetic alopecia, with a combination of both providing the best clinical response and achieving 100% effectiveness among participants.
10 citations
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November 1993 in “Indian Journal of Dermatology Venereology and Leprology” This report observed that a male developed erythema multiforme linked to both topical and oral minoxidil use for androgenetic alopecia, supported by eruption recurrence with reapplication.
9 citations
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September 2011 in “Cutaneous and Ocular Toxicology” This article presents a case of central serous chorioretinopathy occurring after the use of topical minoxidil solution, but reports no clinical study findings.
5 citations
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July 2020 in “JAMA Dermatology” Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.
5 citations
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January 2015 in “Journal of clinical & experimental dermatology research” This study found that the MorrF topical solution combination showed significantly better hair growth improvements than Minoxidil alone in male patients with Androgenetic Alopecia.
4 citations
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March 1991 in “Dermatitis” This study observed that allergic contact dermatitis is frequently associated with the use of topical minoxidil for hair loss, suggesting that patch tests could help identify sensitized patients.
1 citations
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August 2018 in “Journal of The American Academy of Dermatology” Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.
1 citations
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May 2014 in “European Journal of Inflammation” This study found that a topical lotion containing minoxidil, hydrocortisone butyrate, and 17α-estradiol improved or stabilized frontal fibrosing alopecia in 35 out of 40 women over 36 months.
1 citations
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January 1991 in “Journal of Dermatological Treatment” In this study, 2% minoxidil applied topically did not alter scalp sebum levels, despite promoting hair growth in some participants.
March 2026 in “Journal of Dermatological Treatment” In this randomized, double-blind, placebo-controlled trial, topical 3% minoxidil was found to significantly improve facial hair density and diameter, quality of life, and patient satisfaction in transgender men on stable gender-affirming hormone therapy, with minimal adverse events compared to placebo.
December 2025 in “PubMed” In this study, researchers found that a propylene glycol-free and alcohol-reduced topical foam containing minoxidil and finasteride remained chemically, physically, and microbially stable for 180 days when stored properly at room temperature in light-resistant containers.
December 2025 in “Saudi Pharmaceutical Journal” This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.
October 2025 in “Journal of Craniofacial Surgery” In this study, microneedling followed by topical 2% chitosan significantly improved hair growth parameters in patients with androgenetic alopecia, comparable to results with 5% minoxidil, but a small sample size limits definitive conclusions on their relative efficacy.
August 2025 in “Indian Dermatology Online Journal” This study found that combining topical minoxidil with phototherapy significantly improved pigmentation and reduced vitiligo severity compared to placebo, as measured by VASI scores over 12 weeks, though the sample size was small and follow-up short.
April 2025 in “Acta Dermato Venereologica” This review evaluates 21 studies on minoxidil-induced allergic contact dermatitis, finding that some patients with contact dermatitis symptoms like erythema and pruritus are sensitized to minoxidil or its vehicle components and should consider patch testing and alternative formulations for proper management.
March 2025 in “Drug Development Research” In this study, researchers developed a novel topical gel combining minoxidil and JAK inhibitor tofacitinib, which effectively enhanced hair follicle growth and reduced local inflammation in mice with alopecia areata, suggesting a new approach for treating this condition.
January 2025 in “Dermatology Practical & Conceptual” This study found topical finasteride and minoxidil both improved hair loss clinically and trichoscopically more effectively than spironolactone in women with female pattern hair loss.
January 2025 in “International Journal of Trichology” This study found both topical spironolactone and topical minoxidil to be effective and safe treatments for female pattern hair loss, with mild to marked improvement observed over six months in both treatment groups, though more side effects were noted with minoxidil.
December 2024 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that the combination of platelet-rich plasma with topical minoxidil and finasteride was more effective in treating androgenetic alopecia than the conventional minoxidil and finasteride therapy alone.
October 2024 in “Journal of Drugs in Dermatology” This study found that a combination of topical finasteride 0.25% with minoxidil 5% was more effective than using topical minoxidil 5% alone for treating male pattern androgenic alopecia over a 12-week period.
January 2024 in “International Journal of Dermatology Research” This randomized clinical trial found that both topical ethinylestradiol 0.01% combined with minoxidil 2% and minoxidil 2% alone were similarly effective in enhancing hair growth for female pattern hair loss, though minoxidil alone was better tolerated with fewer side effects over 24 weeks.
December 2023 in “Siriraj Medical Journal” This study found that 5% azelaic acid solution and 2% minoxidil solution both significantly increased hair density and shaft diameter in women with FPHL, with no significant differences between them.
November 2023 in “PubMed” This study found that treating mice with naringenin, alone or combined with minoxidil, significantly increased hair growth and follicle diameter and quantity, likely due to its antioxidant and anti-inflammatory properties.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
April 2022 in “UNESP Institutional Repository (São Paulo State University)” This study found that the combination of topical minoxidil and oral biotin significantly increased hair growth speed and density in healthy men, while neither intervention alone had a significant effect.
December 2022 in “Archives of Dermatological Research” This study found that topical cetirizine increased hair shaft thickness and improved clinical outcomes from the patients' perspective in female androgenetic alopecia compared to minoxidil alone, with similar side effect profiles.
July 2021 in “Indian journal of drugs in dermatology” In this study, the combination of intradermal meso-solution and topical 5% minoxidil significantly increased hair re-growth in men with androgenetic alopecia compared to minoxidil alone.
September 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 2-year-old girl with severe alopecia areata experienced significant hair regrowth after 37 weeks of treatment with dupilumab and minoxidil, but the combination of treatments and possible spontaneous recovery mean the improvement cannot be solely credited to dupilumab.
September 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study describes a case where a 2-year-old girl with severe alopecia areata showed marked hair regrowth after 37 weeks of treatment with dupilumab and minoxidil, but due to concurrent therapies and potential spontaneous recovery, improvements cannot solely be attributed to dupilumab.
June 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Combining Procapil with minoxidil improves hair growth in men with hair loss.