Comparative Efficacy of Topical Chitosan and Minoxidil in Hair Loss: A Controlled Study With Microneedling

    October 2025 in “ Journal of Craniofacial Surgery ”
    Jovian Wan, A. S. Sydorchuk, Irwan Junawanto … Kyu‐Ho Yi
    Studysummary In this study, microneedling followed by topical 2% chitosan significantly improved hair growth parameters in patients with androgenetic alopecia, comparable to results with 5% minoxidil, but a small sample size limits definitive conclusions on their relative efficacy.
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    Research cited in this study 7

    1. A Prospective Study of Exosome Therapy for Androgenetic Alopecia Aesthetic Plastic Surgery · 2025
    2. Chitosan Stimulates Root Hair Callose Deposition, Endomembrane Dynamics, and Inhibits Root Hair Growth Plant Cell & Environment · 2024
    3. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    4. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    5. Microneedling for the Treatment of Hair Loss Journal of The European Academy of Dermatology and Venereology · 2017
    6. Low-Level Laser Therapy for Treatment of Hair Loss Lasers in Surgery and Medicine · 2013
    7. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013

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