Clinical and Trichoscopic Evaluations of Topical Finasteride 1%, Topical Spironolactone 5%, and Minoxidil 5% in Female Pattern Hair Loss Treatment

    January 2025 in “ Dermatology Practical & Conceptual ”
    Naglaa Mohamed El Sayed, Eman H. Elmorsy, Tarek Hussein, Eman M. Hassan
    Studysummary This study found topical finasteride and minoxidil both improved hair loss clinically and trichoscopically more effectively than spironolactone in women with female pattern hair loss.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 35

    1. Dermoscopic Evaluation of the Efficacy of Combination of Topical Spironolactone 5% and Minoxidil 5% Solutions in the Treatment of Androgenetic Alopecia: A Cross-Sectional Comparative Study Journal of Cosmetic Dermatology · 2022
    2. Topical Finasteride for Male and Female Pattern Hair Loss: Is It a Safe and Effective Alternative? Journal of Cosmetic Dermatology · 2022
    3. Development and Validation of a Dermoscopic Severity Score for Female Pattern Hair Loss Skin appendage disorders · 2021
    4. Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
    5. Comparative Study of Efficacy of Topical Minoxidil Versus Topical Minoxidil With Finasteride in Androgenetic Alopecia International Journal of Research in Dermatology · 2021
    6. A Novel Topical Combination of Minoxidil and Spironolactone for Androgenetic Alopecia: Clinical, Histopathological, and Physicochemical Study Dermatologic Therapy · 2020
    7. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients Dermatology practical & conceptual · 2020
    8. The Use of Trichoscopy to Assess the Efficacy of Topical Minoxidil 2% Solution in Patients with Female Pattern Hair Loss Zagazig university medical journal · 2019
    9. Efficacy and Safety of a New 10% Topical Minoxidil Versus 5% Topical Minoxidil and Placebo in the Treatment of Male Androgenetic Alopecia: A Trichoscopic Evaluation Journal of Dermatological Treatment · 2019
    10. Dermoscopic Pre- And Post-Treatment Evaluation In Patients With Androgenetic Alopecia On Platelet-Rich Plasma—A Prospective Study Journal of Cosmetic Dermatology · 2018
    11. Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent Dermatologic Therapy · 2018
    12. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    13. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    14. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    15. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    16. Relevance of Trichoscopy in the Differential Diagnosis of Alopecia: A Cross-Sectional Study from North India Indian Journal of Dermatology, Venereology and Leprology · 2016
    17. Trichoscopic Findings of Androgenetic Alopecia and Their Association with Disease Severity Journal of Dermatology · 2015
    18. Scalp Dermatoscopic Findings in Androgenetic Alopecia and Their Relations with Disease Severity Annals of Dermatology · 2014
    19. Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role? Skin Pharmacology and Physiology · 2013
    20. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    21. Trichoscopy Dermatologic Clinics · 2012
    22. Dermoscopy Findings in Female Androgenetic Alopecia Anais Brasileiros De Dermatologia · 2012
    23. Female Pattern Hair Loss: Clinical and Laboratory Findings and Trichoscopy Depending on Disease Severity International Journal of Trichology · 2012
    24. Clinical Evaluation of Alopecias Using a Handheld Dermatoscope Journal of The American Academy of Dermatology · 2011
    25. A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women Journal of The American Academy of Dermatology · 2011
    26. Scalp Dermoscopy of Androgenetic Alopecia in Asian People Journal of Dermatology · 2009
    27. Dermoscopy in Female Androgenic Alopecia: Method Standardization and Diagnostic Criteria International Journal of Trichology · 2009
    28. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    29. Efficacy of 5% Minoxidil Versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss American Journal of Clinical Dermatology · 2007
    30. Videodermoscopy in the Evaluation of Hair and Scalp Disorders Journal of The American Academy of Dermatology · 2006
    31. The Histopathology of Noncicatricial Alopecia Seminars in Cutaneous Medicine and Surgery · 2006
    32. Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for Their Modes of Action in Hair Follicles Journal of Investigative Dermatology · 2005
    33. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    34. Histological Features of Peripilar Signs Associated with Androgenetic Alopecia Archives of Dermatological Research · 2004
    35. Topical Finasteride in the Treatment of Androgenic Alopecia: Preliminary Evaluations After a 16-Month Therapy Course Journal of Dermatological Treatment · 1997

    Related research 8

    1. Oral Finasteride (5 mg and 2 mg) Versus Topical Minoxidil 5% in Female Pattern Hair Loss Clinical Dermatology Review · 2025
    2. Comparative Study of Topical Minoxidil (5%) Plus Finasteride (0.1%) Versus Platelet-Rich Plasma Plus Topical Minoxidil (5%) Plus Finasteride (0.1%) in Patients with Androgenic Alopecia Asian Journal of Pharmaceutical and Clinical Research · 2024
    3. Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review Cosmoderma · 2021
    4. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    5. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    6. Hair Loss in Women with Hyperandrogenism: Four Cases Responding to Finasteride Journal of The American Academy of Dermatology · 2002
    7. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979
    8. Minoxidil-Induced Hypertrichosis: Treatment with Calcium Thioglycolate Depilatory PubMed · 1977