Efficacy and Safety of Topical 3% Minoxidil for Facial Hair Enhancement in Transgender Men: A Randomized, Double-Blind, Placebo-Controlled Trial

    March 2026 in “ Journal of Dermatological Treatment ”
    Kantarat Wattanawinitchai, Cherrin Pomsoong, Yanisa Ratanapokasatit, Poonkiat Suchonwanit
    Studysummary In this randomized, double-blind, placebo-controlled trial, topical 3% minoxidil was found to significantly improve facial hair density and diameter, quality of life, and patient satisfaction in transgender men on stable gender-affirming hormone therapy, with minimal adverse events compared to placebo.
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    Research cited in this study 19

    1. Efficacy and Safety of Twice-Weekly and Thrice-Weekly Dutasteride Compared to Finasteride in Men with Androgenetic Alopecia: A Randomized, Investigator-Blind, Active-Controlled, Parallel-Group Pilot Study JAAD International · 2025
    2. Efficacy of Topical Minoxidil in Enhancing Beard Growth in Transgender Individuals Assigned Female at Birth on Gender Affirming Hormone Therapy Journal of endocrinological investigation · 2024
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    6. Characterizing the Role of Facial Hair in Gender Identity and Expression Among Transgender Men Journal of the American Academy of Dermatology · 2021
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