Faculty Opinions Recommendation of Topical Minoxidil Reported Hair Discoloration: A Cross-Sectional Study
August 2023
in “
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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TLDR Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
The cross-sectional study discussed in this article investigated the link between minoxidil use and hair discoloration. Using two validated questionnaires, the study found that hair discoloration was more common among long-term minoxidil users and those with a family history of graying hair. Despite minoxidil being a safe and well-tolerated medication, the study highlighted the need for further research into its minor side effects, such as changes in hair pigmentation, due to potential interactions with melanogenesis stimulators, vitamin supplements, and anti-inflammatory drugs. While minoxidil remains a safe and effective treatment for androgenic alopecia, dermatologists are advised to report these potential adverse effects for further study.
