June 2025 in “International Journal of Research in Dermatology” In this case series, researchers observed that combining 0.1% tretinoin gel with 5% minoxidil over 90 days improved hair growth and patient satisfaction in androgenetic alopecia patients who did not previously respond to minoxidil alone, with significant increases in hair count, density, and quality.
This study evaluated the stability of multiple active ingredients in TrichoSol™ for use in alopecia treatments, finding varying stability durations at room temperature—up to 180 days for some ingredients—supporting its use as a compounding vehicle in personalized therapies.
In this study, researchers found that finasteride induces dysregulation of genes related to neuropsychiatric disorders, including the HOMER-3 gene associated with dementia, and propose exploring craniosacral osteopathic therapy's potential to modulate this gene's methylation profile and alleviate related symptoms.
April 2025 in “Health and Society” This paper reviews the development of treatments for androgenic alopecia by analyzing historical data and published methods, focusing on the evolution of techniques to address this common hair loss condition.
April 2025 in “Archives of Dermatological Research” This study found that in patients with androgenetic alopecia, microneedling therapy led to significantly higher treatment adherence compared to medication, with improved adherence linked to factors like age, education, income, reduced side effects, and enhanced treatment efficacy.
March 2025 in “Stem Cell Research & Therapy” This study found that microneedles containing magnetic intracellular vesicles and tremella polysaccharide improved the hair microenvironment and accelerated hair regeneration in mice with androgenic alopecia.
March 2025 in “Carolina Digital Repository (University of North Carolina at Chapel Hill)”
March 2025 in “Buletin Veteriner Udayana” In this case report, a 2.5-year-old cat with scabies and bacterial pneumonia showed significant improvement in symptoms and hair regrowth following a treatment regimen including ivermectin, amoxicillin with clavulanic acid, diphenhydramine, methylprednisolone, and supportive therapies over 100 days.
February 2025 in “Buletin Veteriner Udayana” In this case report, the 14-day treatment with ivermectin, sulfur baths, antihistamines, and supplements resulted in significant recovery in a cat with scabies and sporotrichosis, except for persistent alopecia on the ear pinna. The authors recommend maintaining a clean environment to prevent reinfection.
January 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil alone is effective for treating hair loss, but combining it with dutasteride or finasteride may offer better results.
January 2025 in “Frontiers in Genetics” In this study, researchers reported significant hair growth in an 8-year-old with hypotrichosis simplex of the scalp after treatment with a combination of oral botanical extracts and minoxidil, marking the first documented use of botanical extracts as a potential therapeutic approach for this condition.
In this narrative review, researchers evaluated existing literature on the treatment of frontal fibrosing alopecia, finding that while no curative treatment exists, clinical improvements can be achieved through personalized and combined therapy approaches.
January 2025 in “Indian Journal of Unani Medicine” This case study observed that a Unani medicine regimen significantly improved hair shedding and quality of life in a 24-year-old female with Telogen Effluvium following a febrile illness, showing potential effectiveness and safety in this context.
January 2025 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” This review discusses the promising role of JAK inhibitors in managing alopecia areata, reporting significant hair regrowth and acceptable safety profiles but noting the need for further research on dosing and long-term safety.
January 2025 in “International journal of research and scientific innovation” This critique of a 2019 study highlights the potential of a liposomal hydrogel for delivering Minoxidil and Tretinoin to treat androgenetic alopecia, but underscores the need for in vivo trials and further stability and interaction analysis to validate its promise.
December 2024 in “Biological and Clinical Sciences Research Journal” In this study, injectable platelet-rich fibrin (I-PRF) was found to be more effective than platelet-rich plasma (PRP) at improving hair growth outcomes and patient satisfaction for androgenic alopecia.
October 2024 in “Zagazig University Medical Journal” This clinical trial found that transdermal delivery of 5-Fluorouracil using fractional CO2 laser resulted in a significantly better treatment response in alopecia areata patients compared to intralesional injections of the same drug, with a greater reduction in the Severity of Alopecia Tool Score.
October 2024 in “Benha Journal of Applied Sciences” This study of fifty female patients with frontal fibrosing alopecia in Egypt found that it is a complex condition with no definitive treatment, as it often co-occurs with lichen planus and thyroid issues.
October 2024 in “Journal of Education Health and Sport” This article reviews treatment options for Alopecia Areata, concluding that topical corticosteroids are effective for mild cases, while systemic therapies are advised for moderate to severe cases.
October 2024 in “Asian Journal of Pharmaceutical and Clinical Research” This study at Gajra Raja Medical College found that topical methotrexate with tretinoin was more effective but not significantly better than betamethasone with tretinoin for treating alopecia areata over six months, with similar safety profiles between the treatments.
September 2024 in “Cureus” This case report describes how changing treatment from adalimumab to guselkumab successfully controlled both pustulotic arthro-osteitis and paradoxical skin reactions in a patient with palmoplantar pustulosis.
September 2024 in “Health Problems of Civilization” This study describes the efficacy of oral isotretinoin in treating severe, hormonal, and treatment-resistant acne, noting significant side effects that depend on dose and duration, including teratogenic risks and common issues like skin dryness, while underscoring the importance of systematic monitoring to mitigate adverse effects.
September 2024 in “Journal of the American Academy of Dermatology” This study found that both fractional and excimer lasers are effective in increasing hair density and promoting regrowth in various types of alopecia, although further trials are needed to compare their efficacy to more traditional treatments.
September 2024 in “Journal of Family Medicine and Primary Care” This study found that primary health physicians in Saudi Arabia generally have low knowledge and practice scores regarding the use of vitamins and minerals for treating hair loss, with no significant difference between more or less experienced doctors.
August 2024 in “Journal of Clinical Medicine” This study evaluates the effectiveness of hydroxychloroquine in treating lichen planopilaris, suggesting varying success based on a real-life retrospective analysis.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a nine-year-old child with vitiligo and alopecia areata was successfully treated with upadacitinib and UVB, resulting in a significant reduction in the affected areas, suggesting a promising treatment approach for similar pediatric cases.
July 2024 in “The Journal of Dermatology” This study among patients with severe alopecia areata in South Korea found that 93.4% received pharmacological treatment, with 71.0% achieving hair regrowth and 59.2% experiencing major regrowth, but highlighted a critical unmet need for more effective treatment strategies.
July 2024 in “Journal of Investigative Dermatology” Treating gastrointestinal issues can reduce rosacea flares, and treating rosacea can lower gastrointestinal problems.
June 2024 in “Research Square (Research Square)” This study demonstrated that in mice, the absence of Jagged-1 expression in skin-resident regulatory T cells significantly delays wound healing by reducing the accumulation of neutrophils, highlighting the role of Jagged-1 in coordinating immune cell recruitment during injury.
This case study reports that a man with severe patch-type alopecia areata initially responded to baricitinib treatment but experienced a relapse despite ongoing therapy.