Treatment of Androgenetic Alopecia with Low Dose Oral Minoxidil Monotherapy Compared to Combination Therapy with Dutasteride or Finasteride

January 2025 in “ Journal of the American Academy of Dermatology ”

Ambika Nohria, Deesha Desai, Michelle Sikora, Akshay Pulavarty, Anna Brinks, Carli D. Needle, Avrom S. Caplan, Jerry Shapiro, Kristen Lo Sicco

androgenetic alopecia low-dose oral minoxidil minoxidil dutasteride finasteride antiandrogens 5α-reductase inhibitors AGA LDOM Propecia Avodart Rogaine

TLDR Low-dose oral minoxidil alone is effective for treating hair loss, but combining it with dutasteride or finasteride may offer better results.

The study investigates the efficacy and safety of low-dose oral minoxidil (LDOM) monotherapy compared to combination therapy with antiandrogens, such as dutasteride or finasteride, for treating androgenetic alopecia (AGA). While LDOM is recognized as a safe and effective off-label treatment, finasteride and dutasteride are commonly used as antiandrogen 5α-reductase inhibitors. The study aims to explore the benefits of combining these treatments, as the advantages of such combinations have not been thoroughly examined. The research highlights the need for further exploration into the potential enhanced outcomes of combination therapy for AGA.

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7 / 7 results

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research Comparative Study of Topical Minoxidil (5%) Plus Finasteride (0.1%) Versus Platelet-Rich Plasma Plus Topical Minoxidil (5%) Plus Finasteride (0.1%) in Patients with Androgenic Alopecia

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research Combination Therapy with Oral Minoxidil and Dutasteride in the Treatment of Male Patterned Baldness: A Case Report

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Using oral minoxidil and dutasteride together can quickly increase hair growth and volume with minimal side effects.

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

54 citations, May 2018 in “Journal of The European Academy of Dermatology and Venereology”

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Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

research Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

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Finasteride and minoxidil together work best for male hair loss.

A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia

Treatment of Androgenetic Alopecia with Low Dose Oral Minoxidil Monotherapy Compared to Combination Therapy with Dutasteride or Finasteride

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research Comparative Study of Topical Minoxidil (5%) Plus Finasteride (0.1%) Versus Platelet-Rich Plasma Plus Topical Minoxidil (5%) Plus Finasteride (0.1%) in Patients with Androgenic Alopecia

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research Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

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