Treatment Challenges in Alopecia Areata: Insights From a Case of Baricitinib Therapy Failure

    June 2024 in “ Cureus ”
    Deesha Desai, Ambika Nohria, Kristen I. Lo Sicco, Jerry Shapiro
    TLDR Baricitinib may not always prevent relapse in alopecia areata.
    Alopecia areata (AA) is a difficult condition to treat, traditionally managed with corticosteroids and immunosuppressants. The FDA's approval of baricitinib, a Janus kinase inhibitor (JAKi), was a major advancement, showing promising results in clinical trials. However, this article discusses a rare case of a 30-year-old male with severe patch-type AA who, despite initially responding well to baricitinib, experienced a relapse while still on the treatment. This case highlights the challenges and potential limitations of baricitinib therapy in AA management.
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      community 2 and 1/2 months, prescribed 1.25mg oral min daily

      in Progress Pictures  6 upvotes 5 months ago
      The user is treating alopecia areata with 1.25mg oral minoxidil daily and topical mometasone furoate, considering increasing the dose or adding finasteride, though finasteride is not typically used for this condition. A gluten-free diet is suggested, and alternatives like Olumiant are mentioned.

      community Olumiant active ingredient Baricitinib

      in Research/Science  1 upvotes 3 years ago
      The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 2 years ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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