This chapter reviews current and future strategies for identifying ligands and functions of orphan G protein-coupled receptors, but it reports no new experimental results.
January 2019 in “Springer eBooks” PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.
April 2016 in “Plastic and reconstructive surgery. Global open” This article from the PRS Global Open and ASPS Education Network does not present any new research findings; it likely serves as an introductory or descriptive overview.
This study reviewed and reclassified 37 cases of primary scarring alopecia using histological methods to achieve more accurate diagnoses within subtypes like lupus erythematosus and lichen planopilaris.
January 2011 in “International Journal of Trichology” The conference highlighted new diagnostic tools, the role of genetics in hair loss, and emerging treatments.
67 citations
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August 2007 in “American Journal of Pathology” This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.
January 2001 in “Dermatologic Surgery” The letters discussed medical tools, costs, treatment efficacy, and patient care complexities.
421 citations
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January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
January 2023 in “International Journal of Pharmaceutical and Clinical Research” This review highlights the potential of follicular targeting as a novel approach for treating hirsutism, focusing on its ability to improve outcomes and reduce side effects, but reports no new clinical results.
This chapter discusses the role of orthognathic surgeons in facial feminization surgery, focusing on procedures such as forehead reduction and orbital rim contouring, but reports no new clinical results.
June 2020 in “Journal of Investigative Dermatology” This study found that human hair follicle dermal papilla cells and keratinocytes self-assembled differently in 3D spheroid co-cultures, providing insights into cell distribution and organogenesis during skin regeneration.
March 2009 in “Medical & surgical dermatology” Women with androgenetic alopecia have fewer terminal hairs, phenol in nail surgery is safe, and a new hair transplant method is faster and less damaging.
29 citations
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March 2012 in “Stem Cell Research & Therapy” This article explores questions about dormant hematopoietic stem cells and suggests avenues for future research, but does not present new experimental results.
7 citations
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July 2008 in “Experimental Dermatology” This study identified molecular elements controlling the expression and stabilization of THH protein in hair follicle cells, revealing key mechanisms that support hair shaft development in mice.
6 citations
,
June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
4 citations
,
April 2011 in “International Journal of Radiation Biology” This study found that a newly developed mouse ear punch model effectively demonstrated that radiation significantly delays wound healing and may be used to study combined radiation and wound injury mechanisms.
January 2018 in “Springer eBooks” Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.
303 citations
,
October 2000 in “Nature” This study found that RXRα plays a critical role in hair cycling and keratinocyte functions in mice, likely through its interaction with VDR in epidermal cells.
5 citations
,
March 2017 in “Immunology and Cell Biology” This review discusses recent advances in biomedical imaging for cancer research, particularly highlighting improved imaging tools for studying solid tissue malignancies, and reports no new clinical results.
53 citations
,
October 2003 in “Developmental Biology” This study in mice found that overexpressing Sonic Hedgehog in basal cells caused skin anomalies and a lack of certain hair fibers, underscoring its key role in hair follicle development.
49 citations
,
May 2020 in “Journal of Clinical Investigation” Exosomes are crucial for protecting sensory hair cells in the inner ear.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
143 citations
,
May 2017 in “Nature cell biology” This study found that the transcription factor Gata6 regulates the sebaceous duct lineage identity and plays a crucial role in epidermal wound healing by enabling dedifferentiation and broader lineage capabilities in post-mitotic cells.
18 citations
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August 2015 in “International Journal of Molecular Sciences” This study developed an efficient method for isolating and enriching multipotent ovine hair follicle stem cells, which may aid in research on the ovine hair cycle and future wool production.
This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.
1010 citations
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August 2000 in “Cell” In this study, researchers found that hair follicle stem cells in mice can generate both hair follicle and epidermis cells, highlighting their potential bipotency.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
214 citations
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April 2017 in “Cell” This study found that micro-niches within hair follicles create heterogeneity among stem cells and transit-amplifying cells, leading to specialized progenitors that control tissue morphogenesis and regeneration.
68 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests a regulatory model where HOXC13 activates Foxn1, affecting hair and nail differentiation, supported by similarities in Hoxc13(tm1Mrc) and Foxn1(nu) mice phenotypes and gene expression patterns.
32 citations
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August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.