Primary Scarring Alopecias: Review of Histopathological Findings of 37 Patients from the Department of Dermatology at the Hospital das Clínicas, Faculty of Medicine, University of São Paulo from 2000 to 2005

    January 2011
    Emanuella Rosyane Duarte Moure
    Image of study
    TLDR Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.
    The study reviewed histopathological findings from 37 patients with primary cicatricial alopecias at the Dermatology Department of the Hospital das Clínicas, University of São Paulo, from 2000 to 2005. It reclassified cases based on specific histological criteria, identifying conditions such as discoid lupus erythematosus, lichen planus pilaris, pseudopelade of Brocq, folliculitis decalvans, and dissecting folliculitis. The study concluded that systematic evaluation using routine stains allowed for accurate diagnosis even in late or non-inflammatory phases. It emphasized the complexity of diagnosing cicatricial alopecias and the importance of thorough scalp examination and biopsy, highlighting the need for multiple biopsy techniques to capture comprehensive diagnostic information.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 282 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community We need to keep these snake oil companies accountable.

      in Treatment  121 upvotes 5 months ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

    Similar Research

    5 / 1000+ results