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Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

The document concludes that transsexual individuals often experience improved quality of life after transitioning, despite higher risks of psychiatric issues and mortality.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Gender identity can be more diverse than just male or female.

Hair loss in women is complex to diagnose and treat, and hair restoration should be done by experts. Using minoxidil before surgery can help manage post-surgery hair shock loss. The Follicular Unit Transplantation method is recommended for women due to its speed, no need for shaving, and better graft quality. Strategies like L, T, and reverse L patterns can help restore central hair density, and regenerative methods can improve graft survival in hair transplants.

Exogenous testosterone use may be linked to developing hidradenitis suppurativa.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Chromosomal differences affect how muscle cells respond to testosterone.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

The healthcare for transgender veterans could be better with a more unified team approach.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.