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    Glossary Gene Transcription

    process where DNA is converted into RNA

    Gene transcription, also known simply as transcription, is the process by which a cell converts a segment of DNA into RNA. This is a crucial step in gene expression, where the information encoded in a gene is used to produce a functional product, typically a protein. During transcription, an enzyme called RNA polymerase reads the DNA sequence of a gene and synthesizes a complementary RNA strand, which can then be translated into a protein or serve other functions within the cell.

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    1. The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1 Journal of Biological Chemistry · 2000 · 119 citations
    2. Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep BMC Biology · 2021 · 112 citations
    3. Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus) PLoS ONE · 2013 · 81 citations
    4. ROOT HAIR DEFECTIVE SIX‐LIKE4 (RSL4) promotes root hair elongation by transcriptionally regulating the expression of genes required for cell growth New phytologist · 2016 · 75 citations
    5. Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype Developmental Dynamics · 2000 · 75 citations
    6. Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures Genomics · 2010 · 61 citations
    7. Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis Development · 2011 · 59 citations
    8. Analyses of histological and transcriptome differences in the skin of short-hair and long-hair rabbits BMC Genomics · 2019 · 59 citations
    9. Transcriptome Profile at Different Physiological Stages Reveals Potential Mode for Curly Fleece in Chinese Tan Sheep PloS one · 2013 · 55 citations
    10. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    11. Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose Animals · 2022 · 46 citations
    12. Transcriptomic analyses of regenerating adult feathers in chicken BMC Genomics · 2015 · 45 citations
    13. Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018 · 37 citations
    14. Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation Differentiation · 2009 · 35 citations
    15. Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome American journal of human genetics · 2020 · 34 citations
    16. Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs Scientific Reports · 2016 · 34 citations
    17. Comparative Transcriptome Analysis Reveals that a Ubiquitin-Mediated Proteolysis Pathway Is Important for Primary and Secondary Hair Follicle Development in Cashmere Goats PLoS ONE · 2016 · 31 citations
    18. A transcriptomic map of murine and human alopecia areata JCI Insight · 2020 · 26 citations
    19. Transcriptomic analysis reveals critical genes for the hair follicle of Inner Mongolia cashmere goat from catagen to telogen PloS one · 2018 · 25 citations
    20. Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat Cells · 2020 · 24 citations
    21. Transcriptomic analysis of human skin wound healing and rejuvenation following ablative fractional laser treatment PLoS ONE · 2021 · 24 citations
    22. Transcriptomic landscape of early hair follicle and epidermal development Cell Reports · 2023 · 23 citations
    23. Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo eLife · 2023 · 23 citations
    24. Transcriptome-based selection and validation of optimal house-keeping genes for skin research in goats (Capra hircus) BMC Genomics · 2020 · 23 citations
    25. Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis Journal of Investigative Dermatology · 2018 · 21 citations
    26. Coregulation of Genetic Programs by the Transcription Factors NFIB and STAT5 Molecular Endocrinology · 2014 · 20 citations
    27. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    28. Transcriptomic regulation of seasonal coat color change in hares Ecology and evolution · 2020 · 18 citations
    29. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile 2016 · 18 citations
    30. The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome BMC Genomics · 2022 · 17 citations