July 2024 in “Chemical Engineering Journal” A new microneedle system with minoxidil nanoparticles effectively promotes hair regrowth with fewer side effects.
June 2024 in “European Journal of Pharmaceutics and Biopharmaceutics” This study reported that using photoacoustic waves to enhance transdermal delivery of encapsulated minoxidil can significantly increase hair growth while reducing treatment frequency and systemic side effects.
May 2024 in “Journal of medicinal food” This review highlights jojoba oil's unique composition and its growing therapeutic applications, noting its antioxidant, anti-acne, antidiabetic, and antibacterial properties, as well as its use in various pharmaceutical formulations.
April 2024 in “The Egyptian Journal of Hospital Medicine” This review highlights that microneedling is an effective and flexible technique for enhancing transdermal drug delivery, with numerous applications in both cosmetic and therapeutic dermatological treatments. The researchers note that further advancements are likely to increase its efficacy and safety.
This source provides an overview of quercetin's therapeutic capabilities in skin wound healing, highlighting its antioxidant and anti-inflammatory benefits but noting its poor solubility limits skin penetration; various delivery strategies have been explored to enhance its effectiveness.
December 2023 in “International Journal of Biological Macromolecules” This study found that MCS nanoparticles improved Minoxidil's hair growth effects in an animal model compared to the commercial formulation, but they were less effective than CS nanoparticles despite showing better solubility with minimal side effects.
November 2023 in “Journal of Drug Delivery Science and Technology” This article reviews the potential of stem cell-derived exosomes as a therapeutic approach for androgenic alopecia, noting their advantages over traditional cell therapy in repairing and regenerating hair follicles to address hair loss.
June 2023 in “Dermatologic Surgery” This review highlights the promising potential of mesotherapy for delivering dutasteride and minoxidil as treatments for androgenetic alopecia, emphasizing the need for more research on drug preparation, delivery, and maintenance to establish its safety and effectiveness.
November 2022 in “Journal of the Endocrine Society” In this case study, a woman with high 25(OH)D levels and persistent symptoms showed decreased parathormone after transdermal estrogen therapy, highlighting the importance of assessing both parathormone and estrogen levels in similar patients.
August 2022 in “Scholars academic journal of pharmacy” This study involved formulating an invasome gel loaded with clotrimazole for treating fungal infections and assessed its various properties like spreadability and in vitro drug diffusion.
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential of microneedles as a pain-free drug delivery method that improves medication distribution while addressing issues associated with traditional transdermal formulations.
May 2022 in “Research Square (Research Square)” This study found that the newly developed transdermal oil body microgel emulsion (OBEME) improved wound healing in mice by enhancing skin permeability, reducing inflammation, and promoting new blood vessel formation and re-epithelialization.
August 2019 in “Key engineering materials” This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.
June 2019 in “Medicine and science in sports and exercise” This case report documents a 20-year-old female runner with recurrent bone stress injuries, concluding they were due to low bone density from uncontrolled Celiac Disease and functional hypothalamic amenorrhea from low energy availability.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
This review discusses the advancements and applications of multiphoton microscopy in dermatology, including its role in imaging skin disease and drug transport, and reports no new clinical results.
January 2013 in “프로그램북(구 초록집)” This study found that home-use microneedle devices combined with 5% minoxidil are not inferior to using 5% minoxidil alone for treating pattern hair loss, and may safely enhance hair growth.
August 2012 in “Open Repository and Bibliography (University of Liège)” This case report found that a dog's progressive alopecia and prostatitis were caused by ingesting a transdermal estradiol cream, emphasizing the need to identify exogenous estrogen sources during evaluation.
January 2012 in “Journal of Cosmetics Dermatological Sciences and Applications” This study found that iontophoresis significantly enhances the skin penetration of magnesium salt of L-ascorbic acid 2-phosphate, especially in hairy mice, compared to passive diffusion.
This study observed that chitosan-decorated PS404-b-PAA63 nanoparticles may enhance skin retention and reduce permeation flux of finasteride, suggesting potential for improved transdermal delivery.
April 2011 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study suggests that polymersomes decorated with chitosan improve the transdermal delivery of finasteride, providing an alternative drug delivery system with higher drug retention in the skin.
August 2010 in “Springer eBooks” Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.
January 2010 in “USFEU Scientific Library (Ural State Forest Engineering University)” This study developed a grooved microneedle platform enabling precise transdermal delivery of triamcinolone acetonide for alopecia areata, achieving accurate dosing by controlling groove position and drug concentration.
May 2008 in “Trends in Urology Gynaecology & Sexual Health” This study found that continuous use of loop diuretics may double the rate of bone loss in elderly men compared to intermittent or non-use.
January 1987 in “Side effects of drugs annual” This chapter reviews dermatological drugs and cosmetics, identifying common allergens and preservatives linked to contact dermatitis without reporting new clinical results.
April 2016 in “International Journal of Drug Delivery” This study found that finasteride ethosome formulations with specific ethanol and soya lecithin concentrations significantly enhanced transdermal drug delivery compared to a potential nanogel.
January 2010 in “West China Journal of Pharmaceutical Sciences” The study found that high-dose intragastric administration of Pterocarpus indcus Willd extracts reduced hair loss and increased hair follicles in a rat model of androgenetic alopecia, but topical application did not show significant effects.
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September 1997 in “Acta Dermato Venereologica” This study found that RXR agonists stimulated human hair follicle growth and survival in vitro, suggesting potential for promoting hair growth in humans.
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July 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fluorescence excitation spectroscopy could be a promising noninvasive tool for assessing the effects of comedolytic agents like retinoids on acne-like lesions in rhino mice.
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” In a C3H mouse model, this study found that topical retinoids can significantly alter hair-cycle dynamics by prolonging the anagen phase and shortening the telogen phase, a reaction connected to increased cellular retinoic acid-binding protein levels.