research Morphologic Markers of Acute and Chronic Stress in Child Abuse
The conclusion is that certain physical signs in the body can indicate past acute and chronic stress, which may help in child abuse investigations.
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research Effect of N-Acetylcysteine on Hair Follicle Changes in Mouse Model of Cyclophosphamide-Induced Alopecia: Histological and Biochemical Study
N-acetylcysteine may prevent hair loss caused by chemotherapy.
research Forensics in Dermatology: Part II
Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.
research Cutaneous Adnexal Cysts Revisited: A Novel Classification Based on Morphological and Molecular Features
The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.
research FGF7-Dependent Inhibition of Human Hair Growth by an Osteopontin-Derived Peptide: A Novel Solution for Hirsutism and Hypertrichosis
A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.
research 17β-Estradiol May Control Human Hair Follicle Growth Also via Up-Regulating the Expression of Cannabinoid Receptor Type 1
17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.
research Specific In Vivo Ablation of Lrig1-Positive Follicular Stem Cells Results in Sebaceous Gland Loss in Mice
Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
research Biological Effects of Electrical Epilation on Human Hair Follicles and Perifollicular Skin Ex Vivo
Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.
research Toxicological Responses in Keratinocyte Interfollicular Stem Cells
Toxins can disrupt skin stem cell balance, causing skin overgrowth or ulceration.
research Toxicological Study on the Health Effects of Long-Term Exposure to Benzene in Benzene Filling Workers, Qassim Region, KSA
Long-term exposure to benzene increases skin diseases, blood disorders, and liver problems.
research Hair Versus Nails: Is There a Place for Other Keratin Matrices?
Nails are a useful alternative to hair for analyzing long-term substance exposure.
research Skin Signs in the Diagnosis of Thallium Poisoning
Thallium poisoning can cause severe neurological symptoms and hair loss.
research Isolation and Structural Identification of a Novel Minoxidil Analogue in an Illegal Dietary Supplement: Triaminodil
A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.
research Comments on 'Maternal–Fetal Safety Evaluation of an Aqueous Extract of Casearia Sylvestris Leaves in Rats' (Nagaoka et al., 2023)
The commentary stresses the importance of using historical control data and proper interpretation in evaluating developmental toxicity.
research Improvement of the Differential Diagnostics of Acute Oral and Inhalation Poisoning by Thallium Compounds, Pathohistology and Treatment Strategy (Based on Group Cases)
Better diagnosis and control of thallium poisoning are needed to prevent severe outcomes.
research Short-Term Biomarkers of Cigarette Smoke Condensate Tumor Promoting Potential in Mouse Skin
The study investigated the effects of cigarette smoke condensates (CSCs) on mouse skin, focusing on hyperplasia and inflammation as short-term biomarkers of tumor promotion. Using a truncated initiation-promotion protocol, the research assessed epidermal thickness, proliferative index, and ornithine decarboxylase (ODC) expression after CSC application. Results showed that CSCs increased these markers, with partial reversibility in interfollicular areas but sustained elevation in perifollicular regions. The study highlighted perifollicular ODC expression as a promising indicator for evaluating CSCs due to its rapid induction, low threshold, and potential to reflect irreversible changes, aligning with the notion that ODC expression is crucial for tumor promotion and that tumors primarily originate in the perifollicular epidermis.
research Effects of 2-Ethylhexanoic Acid on Reproduction and Postnatal Development in Wistar Rats
The study investigated the reproductive toxicity of 2-ethylhexanoic acid (2-EHA) in Wistar rats, with 24 animals per sex per group receiving doses of 100, 300, or 600 mg/kg. Results showed a dose-dependent decrease in fertility, with increased time to mating and total infertility at higher doses. Male rats exhibited decreased sperm quality, with reduced motility and increased abnormal sperm at higher doses. The average litter size decreased by 16% at 600 mg/kg, and while birth weights were unaffected, body weight gain during lactation was slower. Pups showed delayed physical development and abnormal features at higher doses. A single 600 mg/kg dose given to pregnant females reduced implantations and caused resorptions. The study concluded that 2-EHA impaired fertility and delayed postnatal development, likely due to disturbed implantation and teratogenic effects.
research Preliminary Toxicity Profile of Arotinoids SMR-2 and SMR-6 in Male B6D2F1 Mice
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.
research The Potential for Occupational Exposure of Veterinarians to Ketamine Resulting in Positive Drug Tests
Veterinarians could test positive for ketamine from work exposure, not just substance abuse.
research Smoothened Antagonists for Hair Inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research A Method for the Determination of Minoxidil in Hair-Regrowth Formulations by Micellar Electrokinetic Capillary Chromatography
A quick and simple method was created to identify minoxidil in hair-growth products using micellar electrokinetic capillary chromatography.
research Herbal Hair Serum: Design, Development and Evaluation
The document concludes that activating hair roots is important for improving hair growth and preventing hair loss.
research Formulation and Evaluation of Herbal Shampoo from Piper Betel and Psidium Guajava Leaves
The herbal shampoo made from Piper Betel and Psidium Guajava leaves was safe, promoted hair growth, and reduced hair fall.
research UK High Court Revokes Escitalopram Patent; Validity of Second Medical Use Claims Based on Dosage Regimes; Stay of Proceedings Pending EPO Opposition
The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
research Outbreak of Thallium Poisoning Among Iraqi Patients
Thallium poisoning from contaminated cake caused severe health issues in Baghdad, highlighting the need to ban thallium as a rodenticide.
research Effects of Ginseng Saponins on Hair Follicle Growth in C57BL/6 Mouse Models
research Secondary Ion Mass Spectrometric Investigation of Penetration of Coconut and Mineral Oils into Human Hair Fibers: Relevance to Hair Damage
Coconut oil can penetrate hair better than mineral oil, potentially protecting against damage.
research Evaluation of Ameliorative Efficiency of Vitamin E and Saccharomyces Cerevisiae Yeast on Arsenic Toxicity in Black Bengal Kids
Vitamin E, alone or with yeast, helped reduce arsenic poisoning effects in young goats.
research Antioxidant Ability and Hair Growth Effect of Samhwang-Sasimtang in C57BL/6 Model
Samhwang-Sasimtang extract may promote hair growth and act as a natural hair growth agent.
research Antioxidant Activity and Hair Growth Effects of Samhwang-Sasimtang in C57BL/6 Mice
Samhwang-Sasimtang extract promotes hair growth and has strong antioxidant properties.