The Mouse Hairy Ears Mutation Exhibits an Extended Growth (Anagen) Phase in Hair Follicles and Altered Hoxc Gene Expression in the Ears

November 2008 in “ Veterinary Dermatology ”

Sarah E. Mentzer, John P. Sundberg, Alexander Awgulewitsch, Hanna H.-J. Chao, Donald A. Carpenter, Weidong Zhang, Eugene M. Rinchik, Yun You

anagen phase hair follicles Hoxc genes Hoxc8 Hoxc9 chromosome 15 gene expression hair growth hair development growth phase hair roots genetic mechanisms

Studysummary In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.

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