Genetic Control and Involvement in Hair Fiber Traits
December 2011
in “
Springer eBooks
”
Research cited in this study
16 / 16 resultsresearch Autosomal-Dominant Woolly Hair Resulting from Disruption of Keratin 74, a Potential Determinant of Human Hair Texture
A mutation in the KRT74 gene causes tightly curled hair.
research Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans
This study identified genetic variants in the Trichohyalin gene that account for approximately 6% of the variance in hair morphology among Australians of European descent.
research FGFR2 Is Associated With Hair Thickness In Asian Populations
This study found that an SNP in the FGFR2 gene, rs4752566, was significantly associated with hair thickness in Asian populations, suggesting an effect on hair morphology through altered FGFR2 expression levels.
research Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11
research Male-Pattern Baldness Susceptibility Locus at 20p11
In their study, Tim Spector and colleagues identified a new genetic association at chromosome 20p11.22 with male-pattern baldness, confirmed by the increased risk when combined with a known androgen receptor gene variant.
research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form
This study found that a genetic variant in the EDAR gene leads to typical East Asian hair characteristics by increasing signaling output, as shown in transgenic mice experiments.
research Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26
This study located a potential genetic link for androgenetic alopecia on chromosome 3q26, marking an early step in identifying new susceptibility genes for male pattern baldness.
research Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata
This study identified four genetic loci on chromosomes 6, 10, 16, and 18 that may contribute to susceptibility for alopecia areata and suggested shared genetic factors with psoriasis.
research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia
Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
research Keratins of the Human Hair Follicle
More research is needed to understand how hair keratins work and their role in hair disorders.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
This article reviews follicular melanogenesis, detailing how melanin synthesis and its regulation in hair follicles depend on a complex interplay of cellular and molecular mechanisms, but reports no new clinical findings.
research Investigating the Relationship Between the Hair Fiber Proteome and Hair Quality
In this study, researchers linked hair composition and mechanical properties to perceived hair quality, suggesting that hair quality may be genetically determined.
research Genetic Variation at the MC1R Locus and the Time Since Loss of Human Body Hair
Humans lost body hair relatively recently in evolution.
research Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes
This study found no significant genetic association between the 5α-reductase enzyme genes and male pattern baldness, suggesting a polygenic etiology rather than simple inheritance.
research Alopecia Universalis Associated With a Mutation in the Human Hairless Gene
This study identified a missense mutation in the human hairless gene associated with a rare form of recessively inherited alopecia universalis, pinpointed on chromosome 8p12.
research A Gene for Monilethrix Is Closely Linked to the Type II Keratin Gene Cluster at 12q13
This study mapped monilethrix, a hereditary hair and nail disorder, to the type II keratin cluster on chromosome 12q, marking the first primary human hair disorder localization and implicating defects in "hard" keratins.
Related Research
4 / 4 results
research Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells
This study outlines a hair regrowth treatment targeting hair follicle stem cells, 5-alpha reductase pathway, and microinflammation using PDGF and VEGF, but reports no clinical results.
research Fullerene Nanomaterials Potentiate Hair Growth
This study found that fullerene nanomaterials can significantly enhance hair growth and increase hair follicle numbers in both shaved and bald mouse models, as well as in cultured human skin sections.
research Substance P Prolongs Human Hair Growth In Vitro
This study investigated the effects of substance P on human hair growth but found its role in hair follicle physiology remains unclear.
research Towards a Molecular Understanding of Hair Loss and Its Treatment
This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.