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Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.

PI3K/Akt pathway is crucial for hair growth and regeneration.

Rice bran mineral extract may help promote hair growth and prevent hair loss.

Norgalanthamine helps hair cells grow by activating certain pathways related to hair growth.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.