Modulating Aging and Aging-Related Symptoms Using Endogenous Small Molecules

    January 2019
    Min Chai
    Studysummary This study identified that α-ketobutyrate (α-KB) extends lifespan and improves health markers in Caenorhabditis elegans and aged mice by modulating pyruvate metabolism and activating AMPK pathways, with potential implications for human anti-aging treatments.
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