88 citations
,
June 2019 in “Cell reports” This study found that activating autophagy with specific small molecules and drugs can stimulate hair growth by initiating the anagen phase in dormant hair follicles, suggesting a potential treatment for hair loss.
This study identified that α-ketobutyrate (α-KB) extends lifespan and improves health markers in Caenorhabditis elegans and aged mice by modulating pyruvate metabolism and activating AMPK pathways, with potential implications for human anti-aging treatments.
April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reported that small molecules such as α-ketoglutarate, α-ketobutyrate, rapamycin, and metformin may stimulate hair regeneration by activating autophagy pathways.
January 2018 in “Social Science Research Network” This study reports that hair regeneration can be stimulated by small molecules like α-ketoglutarate, α-ketobutyrate, rapamycin, and metformin, which activate autophagy pathways.