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research Research progress and strategies for the biosynthesis of keratinocyte growth factor-2 (KGF-2) in Arabidopsis thaliana

May 2025 in “PeerJ”

This review discusses the potential of using Arabidopsis thaliana to express fusion protein TDP1-KGF-2, aiming to enhance the transdermal delivery of KGF-2 for hair growth applications, despite current challenges with production costs and efficacy.

research K _ATP Channels and Cardiovascular Disease

144 citations , March 2013 in “Circulation Research”

This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.

research KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin

82 citations , May 2009 in “Development”

This study found that downregulation of EGF and KGF signaling is necessary for hair follicle initiation in placodes, revealing a new role for KGF in hair follicle formation in mice.

research Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras‐dependent up‐regulation of KGF expression

51 citations , December 2003 in “The FASEB Journal”

This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.

research Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model

8 citations , February 2025 in “Frontiers in Medicine”

This study suggests that using growth factors and ADSC-conditioned medium can enhance keratinocyte viability and migration in epidermal transplantation, potentially improving chronic wound healing rates with a patient-dependent effect.

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Community Join

3 / 136 results

community 3.5 months minoxidil , 2.5 months 1mg fin update ( also 22 kg weight loss in 6 months! )

10 upvotes 4 years ago

A 21-year-old experienced hair regrowth and improved health after using topical minoxidil, finasteride, and zinc shampoo, alongside lifestyle changes like weight loss and exercise. They also started microneedling and managed seborrheic dermatitis with benzoyl peroxide mixed in shampoo.

community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community Short Peptides for Hair Loss: anyone tried any of these?

14 upvotes 5 months ago

Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.

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Clinics

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Experts

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Hair Transplant Surgeon
Dr. Kgoale Moabelo
Pretoria, South Africa

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Dr. Kgoale Moabelo