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5 / 109 resultsresearch Stimulation of Hair Growth by Small Molecules that Activate Autophagy
This study found that activating autophagy with specific small molecules and drugs can stimulate hair growth by initiating the anagen phase in dormant hair follicles, suggesting a potential treatment for hair loss.
research Exogenous Alpha-Ketoglutaric Acid Alleviates the Rabbit Dermal Papilla Cell Oxidative Damage Caused by Hydrogen Peroxide Through the ERK/Nrf2 Signaling Pathway
This study found that α-ketoglutarate protected dermal papilla cells from oxidative stress by enhancing the Nrf2 pathway and mitigating cell damage through the ERK/Nrf2 axis.
research Causal effects of genetically determined metabolites on androgenetic alopecia: A two‐sample Mendelian randomization analysis
This study used Mendelian randomization analysis to identify Scyllo-inositol and Alpha-ketoglutarate as potential protective factors and Heme and 2-palmitoylglycerophosphocholine as risk factors for androgenic alopecia, suggesting a causal link between these metabolites and the condition.
research Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules
This study identified that α-ketobutyrate (α-KB) extends lifespan and improves health markers in Caenorhabditis elegans and aged mice by modulating pyruvate metabolism and activating AMPK pathways, with potential implications for human anti-aging treatments.
research Hair regeneration by small molecules that activate autophagy
This study reported that small molecules such as α-ketoglutarate, α-ketobutyrate, rapamycin, and metformin may stimulate hair regeneration by activating autophagy pathways.
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2 / 2 resultscommunity What can I use to prepare a lotion that doesn't irritate my scalp or make my hair sticky? (Want to experiment with metformin and Alpha Keto glutarate)
The conversation is about a user who tried dissolving a metformin pill in water for hair treatment but faced issues with hair sticking together. The user is seeking advice on preparing a non-irritating, non-sticky lotion at home, possibly experimenting with metformin and Alpha Keto glutarate.
community Bruteforcing alopecia or the new advent of science progress
Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.
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