Hair Regeneration by Small Molecules That Activate Autophagy

April 2018 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

Min Chai, Meisheng Jiang, Laurent Vergnes, Xudong Fu, Stéphanie C. de Barros, Jing Jiao, Harvey R. Herschman, Gay M. Crooks, Karen Reue, Jing Huang

autophagy α-ketoglutarate α-ketobutyrate rapamycin metformin TOR signaling pathway AMPK signaling pathway hair loss alopecia hormonal dysfunction autoimmunity hair regrowth hair regeneration

From the encyclopedia

Rapamycin →

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

Metformin →

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

Studysummary This study reported that small molecules such as α-ketoglutarate, α-ketobutyrate, rapamycin, and metformin may stimulate hair regeneration by activating autophagy pathways.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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12 / 12 results

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