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research Modulating Aging and Aging-Related Symptoms Using Endogenous Small Molecules

January 2019

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

research Multifunctional Nanomedicine Targeting the 'Seed-and-Soil' of Hair Follicles via Simultaneous Alleviation of Oxidative Stress and Activation of Autophagy for Androgenetic Alopecia Therapy

July 2025 in “Materials Today Bio”

TFC-loaded microneedles effectively promote hair regrowth in androgenetic alopecia.

research Dissecting Hair Breakage in Alopecia Areata: The Central Role of Dysregulated Cysteine Homeostasis

3 citations , May 2024 in “Amino Acids”

Disrupted cysteine metabolism may cause hair breakage in Alopecia Areata, suggesting potential treatments like N-acetylcysteine.

research Autophagy: Guardian of Skin Barrier

8 citations , July 2022 in “Biomedicines”

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

research A State-Of-The-Art Overview On (Epi)Genomics And Personalized Skin Rejuvenating Strategies

December 2025 in “Pharmaceutics”

Personalized skin rejuvenation using genomics shows promise but needs more research.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Is there any new drug that looks promising ?

in Research/Science 26 upvotes 2 years ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 1 year ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

community Research suggests that drugs rapamycin and metformin have hair regeneration properties

2 upvotes 7 years ago

Rapamycin and metformin may have hair regeneration properties. Specific treatments discussed include Minoxidil, finasteride, and RU58841.

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