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research Modulating Aging and Aging-Related Symptoms Using Endogenous Small Molecules

January 2019

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

research Autophagy: Guardian of Skin Barrier

8 citations, July 2022 in “Biomedicines”

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Impairment of Autophagy May Be Associated with Follicular Miniaturization in Androgenetic Alopecia by Inducing Premature Catagen

research Impairment of Autophagy May Be Associated with Follicular Miniaturization in Androgenetic Alopecia by Inducing Premature Catagen

4 citations, December 2020 in “Journal of Dermatology”

Impaired autophagy may cause hair loss by triggering early catagen.

research Hair Regeneration by Small Molecules That Activate Autophagy

April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

Certain small molecules can help regrow hair by turning on the body's cell cleanup process.

research Stimulation of Hair Growth by Small Molecules That Activate Autophagy

88 citations, June 2019 in “Cell reports”

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Is there any new drug that looks promising ?

in Research/Science 25 upvotes 9 months ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 55 upvotes 1 month ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community Research suggests that drugs rapamycin and metformin have hair regeneration properties

2 upvotes 6 years ago

Rapamycin and metformin may have hair regeneration properties. Specific treatments discussed include Minoxidil, finasteride, and RU58841.

community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 7 months ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

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