3 citations
,
June 2025 in “Frontiers in Nutrition” This study reviewed literature on pediatric acrodermatitis enteropathica and found that zinc deficiency occurred in 75.9% of cases, with zinc supplementation showing therapeutic efficacy in 91.4% of patients; however, it was often ineffective in those with underlying metabolic disorders.
August 2022 in “Journal of the American Academy of Dermatology” This review discusses the risk factors, clinical presentation, diagnosis, and management of dermatoses linked to B-complex vitamin deficiencies, including biotin, but does not address risks from over-supplementation.
May 2024 in “Pigment International” In a randomized phase 2b clinical trial, oral ritlecitinib significantly reduced facial vitiligo area scores in patients with active nonsegmental vitiligo compared to placebo, with a favorable safety profile observed over 48 weeks, suggesting its potential as an effective treatment option (Ezzedine et al., 2023).
7 citations
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January 2001 in “PubMed” This study found that vitamin B6 injections over several weeks improved hair condition and reduced hair loss in some women with diffuse alopecia, while calcium pantothenate had no clear positive effect.
July 2026 in “Journal of the American Academy of Dermatology”
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that intralesional triamcinolone acetonide was more effective than Vitamin D supplementation in increasing hair density among alopecia areata patients, although Vitamin D also showed significant hair regrowth in patients with low serum vitamin D levels.
May 2023 in “International Journal of Trichology” In this case report, the researchers described the use of tofacitinib in treating a 14-year-old boy from India with severe alopecia areata, achieving complete hair regrowth within 2 months without serious adverse events, highlighting tofacitinib's potential benefits and safety in adolescent cases.
3 citations
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August 2005 in “Journal of Pediatric Gastroenterology and Nutrition” This case report identifies chronic vitamin A intoxication in a toddler who received excessive vitamin A supplements, resulting in various symptoms and confirmed by liver biopsy findings.
December 2008 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” This study found that antioxidant vitamin treatment improved the hair growth rate in patients with alopecia areata, regardless of the duration of their condition.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
6 citations
,
August 2020 in “Oncology nursing forum” This systematic review reports that prophylactic minocycline and pyridoxine may reduce certain skin toxicities in cancer patients, but evidence quality for various interventions was limited and future research is needed.
10 citations
,
November 1946 in “Journal of the American Medical Association” This study reported that severe hair disturbances in infants and young children are associated with acute vitamin deficiencies in tropical America, unlike the milder cases observed in the United States.
19 citations
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March 2021 in “Experimental and Therapeutic Medicine” This review examines recent literature on isotretinoin's teratogenic effects in both fertile females and males, analyzing its role in causing congenital malformations but provides no new clinical results.
January 1987 in “Toxicological sciences” In this study, SMR-2 and SMR-6, retinoid analogs, were found to be approximately 100 times more toxic than retinoic acid in male mice, primarily affecting skin, immune, and reproductive systems.
9 citations
,
October 1957 in “A M A Archives of Dermatology” In this study, carotene injected into the skin was converted into vitamin A by sebaceous gland cells, where it was not normally detectable.
5 citations
,
January 2009 This study found that Betamethasone was more effective than Tacrolimus and soft paraffin in promoting hair regrowth in patients with mild to moderate patchy alopecia areata.
August 2024 in “Journal of Dermatology & Cosmetology” This case study reports a patient with Rothmund-Thomson syndrome manifesting later in life, who was treated with acitretin to prevent non-melanoma skin cancer associated with the condition.
August 2025 in “International Journal for Vitamin and Nutrition Research” This review highlights the important role of the vitamin B complex in enhancing tissue repair, reducing inflammation, and improving surgical outcomes in plastic and reconstructive procedures by supporting cellular processes such as mitochondrial efficiency, neurotransmitter biosynthesis, and wound healing pathways.
11 citations
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October 1990 in “The Journal of dermatologic surgery and oncology” This review discusses the potential for new retinoids, topical antiandrogens, and alternative therapies to surpass tretinoin in treating cutaneous aging, but reports no clinical results.
29 citations
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December 1953 in “Journal of Investigative Dermatology” March 2023 in “Reactions Weekly” 20 citations
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September 1983 in “Archives of dermatology” This study observed that minimal doses of the arotinoid RO 13-6298 successfully treated two cases of severe psoriasis and psoriatic arthritis unresponsive to traditional therapies, despite some side effects.
7 citations
,
January 2009 in “Journal of Pharmacy Research” This study found that fractions of Tridax procumbens extract demonstrated significant antioxidant activity, comparable to standard ascorbic acid, in laboratory tests.
7 citations
,
September 2013 in “Current Dermatology Reports” This review summarizes existing literature on the safety of commonly used dermatologic medications during pregnancy but does not present new clinical findings, aiming to assist physicians with prescribing decisions.
This study found that various reduced folates effectively penetrated an in vitro skin model, promoted cell proliferation and migration, and may enhance wound healing, suggesting potential for topical treatment in skin conditions.
7 citations
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May 2012 in “Journal of veterinary diagnostic investigation” This study reports that vitamin A deficiency can cause dermatologic issues like alopecia and orthokeratosis in Angus calves, and affected calves improved with vitamin A supplementation.
January 2023 in “Italian journal of dermatology and venereology” This study found that a new oral supplement with sulfurated amino acids and trace elements effectively improved hair growth and reduced hair loss in women with telogen effluvium and mild to moderate androgenetic alopecia.
17 citations
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October 2009 in “Dermatology” This study reported that ultraviolet light treatment from a Kromayer lamp stimulated hair growth in four out of six patients with alopecia, whereas intralesional triamcinolone acetonide had a mixed effect.
January 2021 in “Indian Journal of Paediatric Dermatology” Topical tretinoin 0.025% cream is an effective treatment for Eruptive Vellus Hair Cysts in children.
1 citations
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May 2017 in “Journal of Clinical Oncology” This study found that applying BPM 31543 twice daily was safe, well-tolerated, and showed signs of reducing chemotherapy-induced alopecia in women receiving taxane-based chemotherapy.