13 citations
,
March 2020 in “Genes” This study found that FGF5-/- rabbits exhibited a significant long hair phenotype by prolonging the anagen phase, suggesting FGF5 acts as a negative regulator of hair growth.
13 citations
,
February 2015 in “Journal of Pharmaceutical Sciences” This study found that the polymorphic forms I, II, and III of finasteride can be prepared purely, with form III being identical to what was previously referred to as form X.
11 citations
,
February 2021 in “Biomedicines” This review discusses the role of hair follicle bacterial colonization in immune responses and the pathogenesis of alopecia but reports no new clinical results.
11 citations
,
August 2009 in “Expert Opinion on Drug Discovery” This review discusses current challenges in selective androgen receptor modulator discovery and preclinical evaluation and reports no new results, emphasizing the need for basic research to improve safety and selectivity.
9 citations
,
July 2021 in “Dermatology and Therapy” This review highlights promising recent advances in therapies for epidermolysis bullosa, including gene therapy and stem cell approaches, but reports no definitive cures and emphasizes the need for further research.
9 citations
,
August 2018 in “Biomedical dermatology” This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.
9 citations
,
August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.
6 citations
,
November 2020 in “Molecular and Cellular Endocrinology” This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.
5 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.
2 citations
,
July 2025 in “Discover Chemistry.” This study explored the optimization of phytochemicals from Alstonia boonei to develop potential 5-alpha reductase inhibitors for Benign Prostatic Hyperplasia, finding promising analogs with enhanced binding affinity and stability compared to Finasteride, warranting further experimental validation.
2 citations
,
December 2013 in “Current Oral Health Reports” This review discusses current developments in tooth regenerative therapy, including bioengineered tooth replacements, and emphasizes its potential to fully restore tooth function, but it presents no new clinical results.
2 citations
,
September 2002 in “Dermatologic Surgery” This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.
1 citations
,
September 2025 in “Journal of Ultrasound in Medicine” This study found that AI using YOLOv11 architecture can reliably differentiate between hyaluronic acid and silicone oil cosmetic fillers on ultrasound, achieving high accuracy, whereas identifying calcium hydroxyapatite and polymethylmethacrylate remains less consistent, requiring further improvements.
1 citations
,
March 2025 in “Frontiers in Physiology” This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.
1 citations
,
January 2023 in “Burns and trauma” This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.
This chapter provides an overview of the complex chemical and physical structure of the hair surface, detailing how factors like ethnicity, environmental stress, and cosmetic treatments can alter its properties and influence the adhesion of hair care products.
1 citations
,
January 2020 in “Elsevier eBooks” Forensic medicine is crucial for justice and needs continuous innovation and technology integration.
1 citations
,
January 2016 in “International journal of research in ayurveda and pharmacy” This study found that a herbal formulation optimized with specific concentrations of plant extracts showed promising antifungal activity against Malassezia furfur.
1 citations
,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
March 2026 in “Collagen and Leather” This study found that a newly developed supramolecular FPC hydrogel effectively promotes wound healing through its anti-inflammatory and angiogenic properties, making it a promising material for wilderness first aid due to its storage convenience, sprayability, and ability to speed up wound recovery.
February 2026 in “Frontiers in Immunology” In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.
January 2026 in “Frontiers in Drug Discovery” This study highlights that while advances in dermatology, such as biologics and JAK inhibitors, have improved treatments for conditions like atopic dermatitis and psoriasis, challenges remain, including issues with lasting efficacy and the need for more personalized therapies.
This study found that intrinsic feedback loops are crucial for maintaining the function of human dermal papilla cells during hair growth, highlighting the importance of autocrine signaling and niche reprogramming for advancing hair follicle biology and regenerative therapies for hair loss.
March 2024 in “Drug development & registration” This review highlights the potential of mesenchymal stem cell secretome for developing topical treatments aimed at skin regeneration and treating various diseases, but notes a lack of studies on safety, efficacy, and standardization processes for its clinical use.
January 2024 in “Wiadomości Lekarskie” This study developed an AI-driven method for classifying cells in Follicular Lymphoma cases, achieving a 63% F1-score, precision, and recall in distinguishing centroblasts from other cell types using whole slide images at x20 resolution.
January 2024 in “Wiadomości Lekarskie” This review highlights that AI-based echocardiography in cardiology can enhance diagnostic precision, automation, and therapeutic strategy development, but also presents challenges like diagnostic errors and high costs, indicating a cautious yet promising progression in its adoption.
January 2024 in “Wiadomości Lekarskie” In this study, researchers analyzed the clinical phenotype and primary pathogenic links in patients who survive the acute phase of a critical illness and rely on prolonged intensive care, finding that these patients show persistent inflammation, nutritional deficiencies, and other chronic complications over time.
January 2024 in “Wiadomości Lekarskie” This historical overview commemorates Grzegorz Józef Wojciech Ziembicki, a pioneering surgical leader at Lviv General Hospital, highlighting his contributions to surgical education, innovative procedures, and anesthesia practices during his tenure from 1882 to 1915.
January 2023 in “Brazilian Journals Editora eBooks” Girls with Autism Spectrum Disorder may show different symptoms than boys, leading to missed or delayed diagnoses.
January 2023 in “Marmara University Open Access System” This study found that tideglusib delivered topically in a bacterial cellulose hydrogel showed positive effects on the wound healing of rat palatal mucosa, as observed through macroscopic, histomorphometric, and immunohistochemical evaluations.