Modern Aspects of External Application and Prospects of Using the Secretome of Mesenchymal Stem Cells (Review)

    March 2024 in “ Drug development & registration ”
    Е. О. Бахрушина, I. V. Gravel, O. S. Filippova … O. B. Dobrovolsky
    Studysummary This review highlights the potential of mesenchymal stem cell secretome for developing topical treatments aimed at skin regeneration and treating various diseases, but notes a lack of studies on safety, efficacy, and standardization processes for its clinical use.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on pharmjournal.ru →
    Discuss this study in the Community →

    Research cited in this study 10

    1. Human Adipose-Derived Mesenchymal Stem Cells-Derived Exosomes Encapsulated in Pluronic F127 Hydrogel Promote Wound Healing and Regeneration Stem Cell Research & Therapy · 2022
    2. Functional Enhancement Strategies for Immunomodulation of Mesenchymal Stem Cells and Their Therapeutic Application Stem Cell Research & Therapy · 2020
    3. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth Cells · 2020
    4. HB-EGF Improves the Hair Regenerative Potential of Adipose-Derived Stem Cells via ROS Generation and Hck Phosphorylation International Journal of Molecular Sciences · 2019
    5. Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps Mediators of inflammation · 2019
    6. Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium Dermatologic Surgery · 2019
    7. Overexpression of Nanog in Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Dermal Papilla Cell Activity and Promotes Hair Follicle Regeneration Experimental and Molecular Medicine · 2019
    8. Dental Derived Stem Cell Conditioned Media for Hair Growth Stimulation PLOS ONE · 2019
    9. Conditioned Medium From Human Mesenchymal Stromal Cells: Towards Clinical Translation International Journal of Molecular Sciences · 2019
    10. Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine International Journal of Molecular Sciences · 2017