Studies on the Antimicrobial Activity of Evolvulus Alsinoides, Murraya Koenigii, Lawsonia Inermis, Hibiscus Rosa-Sinensis, Azadirachta Indica Against Malassezia Furfur Using Fractional Factorial Design
January 2016
in “
International journal of research in ayurveda and pharmacy
”
TLDR The study found that a specific combination of five medicinal plants effectively inhibits the fungus that causes dandruff.
The study examined the antimicrobial effects of five medicinal plants on the fungus Malassezia furfur, known to cause dandruff and skin issues. Through fractional factorial design and response surface methodology, the research aimed to create an effective polyherbal antifungal treatment. Results indicated that the optimal mix for inhibiting M. furfur consisted of 0.9 mg Evolvulus alsinoides, 0.41 mg Lawsonia inermis, 1.27 mg Hibiscus rosa-sinensis, 1.61 mg Azadirachta indica, and 1.80 mg Murraya koenigii. The model's significance was supported by an R² value of 0.9435, suggesting that 94% of the response variability was accounted for. The study concluded that this herbal combination could be an effective treatment for dandruff, although the number of samples or participants was not mentioned.
