Indian Medicinal Herbs And Formulations For Alzheimer’s Disease: From Traditional Knowledge To Scientific Assessment

The document reviewed the potential of Indian medicinal herbs in treating Alzheimer's Disease (AD), emphasizing the transition from traditional knowledge to scientific assessment. It highlighted several herbs, including Bacopa monnieri, Centella asiatica, and curcumin from turmeric, for their cognitive and neuroprotective benefits. Bacopa monnieri and Centella asiatica showed promise in enhancing memory and reducing cognitive decline, supported by clinical and experimental studies, including a double-blind, placebo-controlled study with 46 healthy volunteers. Curcumin was noted for its neuroprotective properties, though its clinical efficacy in AD remained unproven. Despite promising preclinical results, the document stressed the need for further clinical evaluation to confirm the efficacy and safety of these herbs in AD treatment. The review also discussed the importance of quality control, understanding herb-drug interactions, and regulatory challenges in developing herbal drugs for Alzheimer's disease.