research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
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90-120 / 1000+ results research Catalytic Antibodies in Normal and Systemic Lupus Erythematosus
Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
research Assessment and Treatment Outcomes of Persistent Radiation-Induced Alopecia in Cancer Patients
Persistent radiation-induced hair loss is dose-dependent, and treatments like topical minoxidil can be effective.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Association Between Interleukin 18 Polymorphisms and Alopecia Areata in Koreans
Certain genetic variations in IL18 may increase the risk of alopecia areata in Koreans.
research Association Between TLR1 Polymorphisms and Alopecia Areata
A specific gene variant (rs4833095) is linked to a higher risk of alopecia areata in Koreans.
research Hair and Scalp Disorders in Women of African Descent: An Overview
The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
research Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence
Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
research Mechanism of Salutary Effects of Finasteride on Post-Traumatic Immune/Inflammatory Response
Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.
research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?
Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Association of Epidemiological and Biochemical Factors with Premature Graying of Hair: A Case-Control Study
Genetics and nutritional deficiencies are key factors in premature graying of hair.
research Hair Shaft Abnormalities After Chemotherapy and Tamoxifen Therapy in Patients With Breast Cancer Evaluated by Optical Coherence Tomography
Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.
research Clinical Features of Systemic Lupus Erythematosus Patients Complicated with Evans Syndrome
SLE patients with Evans syndrome often show blood issues and need careful monitoring and treatment.
research Identification of MicroRNAs Involved in Growth Arrest and Cell Death in Hydrogen Peroxide-Treated Human Dermal Papilla Cells
Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.
research The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives
Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
research Genomewide Differential Expression Profiling of Long Non-Coding RNAs in Androgenetic Alopecia in a Chinese Male Population
Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
research Hairless Up-Regulates TGF-β2 Expression via Down-Regulation of miR-31 in the Skin of Hairpoor (HrHp) Mice
HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
research Innate Immunity and the Regulation and Mobilization of Keratinocyte Stem Cells: Are the Old Players Playing a New Game?
Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
research Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla
Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
research Editorial: Mesenchymal Stromal Cell Therapy for Regenerative Medicine
Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.
research Fibroblast Heterogeneity and Tertiary Lymphoid Tissues in the Kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research Local Inflammation Exacerbates Cutaneous Manifestations in a Murine Autoimmune Pemphigus Model
Local inflammation worsens autoimmune skin conditions by increasing antibody buildup.
research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2
Certain genetic changes in the LSS gene cause a rare skin and hair condition.
research New Insights Into Human Hair: SAXS, SEM, TEM, and EDX for Alopecia Areata Investigations
Alopecia Areata causes significant structural and compositional changes in hair.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research Frontal Fibrosing Alopecia: A Disease Fascinating for the Researcher, Disappointing for the Clinician and Distressing for the Patient
Frontal Fibrosing Alopecia is a poorly understood condition that is hard to treat and causes distressing hair loss.