Thyroid problems can cause hair loss and change hair texture.
32 citations,
March 2021 in “Journal of endocrinological investigation” Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
3 citations,
January 2024 in “Liver International” Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.
60 citations,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
47 citations,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
January 2015 in “Journal of clinical & experimental dermatology research” A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.
1 citations,
January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
46 citations,
September 2016 in “Clinical, Cosmetic and Investigational Dermatology” Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
26 citations,
October 2016 in “Clinics in Dermatology” Hormonal treatments can improve acne, but they come with potential side effects and risks.
7 citations,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
6 citations,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
80 citations,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
53 citations,
September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
44 citations,
November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
16 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
11 citations,
September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations,
July 2020 in “Journal of Cosmetic Dermatology” Sandalore® improves hair growth and quality in people with hair loss.
9 citations,
January 2018 in “Acta dermato-venereologica” A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
70 citations,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
27 citations,
May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
September 2012 in “The Egyptian Journal of Histology” Flutamide caused damage to male rat reproductive organs and may affect fertility.
291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
191 citations,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
114 citations,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
93 citations,
June 2001 in “The Journal of Clinical Endocrinology and Metabolism” Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
31 citations,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
30 citations,
July 2019 in “Endocrinology” Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
28 citations,
January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders” Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.