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Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

KB2115 (eprotirome) can safely extend the hair growth phase without damaging cells or changing hair color.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

Finasteride reduces movement issues in Parkinson's disease rats.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Iron deficiency might contribute to hair loss in women.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.