November 2025 in “PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS” This study found that taurine significantly mitigated DHT-induced androgenetic alopecia in male C57BL/6 mice by promoting hair regrowth, enhancing hair follicle cycle progression, reducing apoptosis, and downregulating key androgen-related signaling pathways, highlighting its potential as a therapeutic candidate for hair loss management.
39 citations
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January 2019 in “Cells” This review discusses the molecular mechanisms of Hutchinson-Gilford progeria syndrome and evaluates current research trends, available mouse models, and prospects for developing therapies, but reports no new clinical findings.
July 2025 in “Journal of Investigative Dermatology” TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
10 citations
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August 2022 in “Journal of clinical sleep medicine” This study found that transgender or gender-nonconforming youth experience higher odds of sleep disorders compared to cisgender peers, but gender-affirming therapy may reduce these odds.
January 2026 in “International Society of Hair Restoration Surgery” This study reports that a novel multimodal approach, combining tattoo machine–assisted drug delivery of hair loss treatments with oral and topical medications, may enhance hair density and thickness in androgenetic alopecia patients, though larger controlled studies are needed to confirm these early findings.
January 2026 in “Journal of Investigative Dermatology” This study found that human γδTregs promoted hair regrowth and restored hair follicle immune privilege in a model of alopecia areata, suggesting potential for cell-based therapy in autoimmune diseases.
13 citations
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May 1993 in “International Journal of Dermatology” This article presents a theory on the causes and development of telogen effluvium and reports no new clinical findings.
November 2025 in “Journal of Investigative Dermatology” TEDAR is crucial for skin cell differentiation and barrier formation.
7 citations
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January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
May 2022 in “European medical journal” This case report highlights a rare instance of gastric trichobezoar, or "Rapunzel syndrome," associated with trichotillomania, characterized by hair accumulation in the stomach of a patient.
October 2025 in “Biomedicines” This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.
January 2023 in “DIGITAL HEALTH” This study found that users of a German direct-to-consumer teledermatology platform for finasteride reported improvements in hair appearance and self-esteem, though 12% experienced treatment-related adverse events.
10 citations
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January 2011 in “Case reports in dermatological medicine” This report documented a successful and sustained hair restoration surgery using follicular unit transplantation for temporal triangular alopecia, lasting over six years.
October 2024 in “Journal of the Endocrine Society” This case report describes a rare conversion from Hashimoto's thyroiditis to Graves' disease in a 23-year-old male, requiring a shift from levothyroxine to methimazole and eventually radioactive iodine therapy.
December 2024 in “Animals” In this study, Tithonia diversifolia extract was found to improve certain digestive parameters in crossbred sheep but did not enhance growth performance, as the improvements in digestion did not translate into increased body weight or feed conversion.
3 citations
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June 2018 in “Internal Medicine” In this study, a patient with Cronkhite-Canada syndrome complicated by severe sepsis and disseminated intravascular coagulation was successfully treated using combined therapies, including recombinant human soluble thrombomodulin, despite the absence of a standard treatment regimen for CCS.
37 citations
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January 1986 in “Carcinogenesis” This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.
2 citations
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January 1997 in “Mapping” This study suggests that Gambogic Amide may act as an anti-hair greying and hair growth-promoting molecule in human hair follicles in vitro by maintaining pigmentation and stimulating hair shaft elongation.
November 2025 in “Indian Journal of Nephrology” In this case study, a 43-year-old male with anti-GBM disease experienced a relapse triggered by hair dye, leading to diffuse alveolar hemorrhage; managing this with plasmapheresis, intravenous immunoglobulins, and rituximab suggests rituximab may be beneficial for relapsing cases.
December 2019 in “Journal of pediatrics & neonatology” This case report discusses the diagnosis and management of temporal triangular alopecia in a pediatric patient experiencing asymptomatic hair loss, emphasizing its nonprogressive nature and poor prognosis for regrowth.
March 2026 in “Bioengineering & Translational Medicine” This study reported that a modified version of Thymosin beta 4, called PEG-rTβ4, demonstrated potential as a treatment for acute myocardial infarction by improving cardiac function and reducing cell death via specific biochemical pathways, suggesting its promise in drug development efforts.
April 2026 in “Cosmetics” In this randomized, double-blind, placebo-controlled trial, researchers found that a multi-targeted cosmetic formulation containing TrinogeniX™ significantly increased hair density and thickness in individuals with androgenetic alopecia without adverse effects, suggesting it as a potential safe and effective treatment option.
August 2024 in “Cell Death and Disease” This study found that toll-like receptor 9 plays a previously unrecognized role in sensing skin injury and influencing tissue repair and regeneration in adult mice by modulating γδT cell migration.
May 2017 in “Journal of The American Academy of Dermatology” An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
November 2025 in “Bioactive Materials” In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.
August 2024 in “Life Science Alliance” This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.
82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
9 citations
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June 2017 in “American journal of ophthalmology. Case reports” This case report identifies a novel CDH3 gene mutation associated with hypotrichosis with juvenile macular dystrophy in a 13-year-old Turkish girl, highlighting implications for future genetic analysis and counseling.
January 2008 in “Annals of Nutrition and Metabolism” This study suggests that a specific region upstream of the TGF-β1 gene may play a key role in androgenetic alopecia by regulating gene expression in a cell-specific manner.
58 citations
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February 2013 in “Journal of Biological Chemistry” This study identifies specific molecular components involved in the intracellular trafficking of LGR5, revealing mechanisms that differ from typical GPCR recycling processes.