TLDR Tattoo machine-assisted drug delivery may improve hair growth in androgenetic alopecia.
The document discusses a novel approach for treating androgenetic alopecia (AGA) using a combined regenerative technique (CRT) that involves tattoo machine–assisted drug delivery, also known as Microinfusion of Medicaments into the Skin (MMP®). This technique integrates controlled scalp microneedling with the direct intradermal deposition of therapeutic agents such as minoxidil sulfate, dutasteride, copper peptides, and platelet-rich plasma, alongside oral minoxidil and topical finasteride. Early clinical experiences indicate that this multimodal approach may improve hair density and shaft thickness while maintaining a favorable safety profile. However, larger controlled studies are necessary to better understand its effectiveness and role in AGA treatment.
February 2025 in “JAAD International” Five monthly sessions of minoxidil-dutasteride-copper peptide tattooing significantly improve hair regrowth in men with androgenetic alopecia.
April 2024 in “JAMA dermatology” Oral minoxidil is as effective as topical minoxidil for male hair loss but has more side effects like excessive hair growth and headaches.
May 2023 in “JAAD international” Minoxidil-dutasteride tattooing can potentially help regrow hair, especially in men who already have some thin hair.
30 citations
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April 2021 in “Journal of The American Academy of Dermatology” Hair transplantation can effectively restore hair in balding areas.
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April 2020 in “Facial Plastic Surgery Clinics of North America” Follicular Unit Excision (FUE) is a popular, safe hair transplant method that avoids scars and has a quick recovery, but requires precise surgical skill.
2 citations
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February 2020 in “Journal of Plastic Surgery and Hand Surgery” Good-looking donor sites for hair transplants usually have higher hair density and thicker hair.
19 citations
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March 2019 in “International Journal of Dermatology” The tattoo machine method safely delivers an average of 1,175 µg/cm² of medication into the skin.
April 2024 in “Cosmetics” Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.
August 2025 in “Plastic and Aesthetic Research” Microneedling can effectively treat hair loss and works well with other treatments, but more research is needed.
January 2025 in “Bright Sky Publications eBooks” Advancements in medical physics and laser technology are improving healthcare but access remains unequal globally.
January 2018 in “Springer eBooks” Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.