Use of Simulation in Error Control in Rasterization

The study explored the role of TrkA, a receptor for nerve growth factor, in hair follicle biology, particularly its expression during the hair cycle and the effects of Gambogic Amide, a selective TrkA agonist, on hair pigmentation and growth. TrkA was found to be highly expressed in melanocytes during the early anagen phase, but its expression decreased in the catagen phase. In vitro experiments showed that Gambogic Amide prevented pigment loss and stimulated hair shaft elongation by activating and migrating melanocytes. The findings suggested that Gambogic Amide could act as an anti-hair greying and hair growth-promoting agent by maintaining hair follicle pigmentation through its action on undifferentiated melanocytes.