December 2023 in “Research in pharmacy” This review underscores the importance of phytotherapeutic compounds and adjuncts in managing polycystic ovarian syndrome but does not present new clinical evidence.
37 citations
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September 2018 in “The Journal of Clinical Endocrinology and Metabolism” This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.
July 2008 in “Journal of Intellectual Property Law & Practice” The UK Intellectual Property Office allows granting of supplementary protection certificates with negative terms.
This study observed that women with PCOS have a higher likelihood of vitamin D deficiency, particularly if they are obese, compared to women without PCOS.
16 citations
,
November 1992 in “Journal of International Medical Research” In this randomized study, ViviScal® significantly outperformed a fish extract in increasing non-vellus hair count and achieving clinical and histological improvement in young males with hereditary androgenic alopecia.
3 citations
,
January 2017 in “Journal of cosmetology & trichology” In this clinical trial, supplementation with Lambdapil® Anti Hair Loss capsules for 6 months significantly improved hair resistance and volume in women and increased the anagen/telogen hair ratio in men, indicating enhanced hair growth compared to the placebo group.
21 citations
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April 2011 in “Physiological Research” In this review, the role of DHT in male-type obesity and metabolic diseases is discussed, with increased levels potentially exacerbating cardiovascular disease risk; the paper reports no new results.
1 citations
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October 2017 in “Food Additives & Contaminants: Part A” This study identified a new minoxidil analogue called triaminodil in an illegal hair-growth supplement, but no data on its chemical, toxicological, or pharmacological properties are available yet.
September 2022 in “Research Square (Research Square)” This study found that while pro-, pre-, and synbiotics may have beneficial effects on certain PCOS-related outcomes, the certainty of this evidence is low to very low.
14 citations
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October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
November 1999 in “Journal of Cutaneous Medicine and Surgery” Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
July 2026 in “Veterinary Medicine and Science” In this study, Quercetin-loaded black seed oil nanoemulsion effectively mitigated testosterone-induced testicular oxidative stress and inflammation in rats undergoing exercise and restraint stress, with improved antioxidant levels and reduced inflammatory markers compared to other treatment groups.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
55 citations
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July 1999 in “Clinics in Sports Medicine” This review discusses recent data on the use of anabolic-androgenic steroids and other steroid compounds and reports no new clinical results.
15 citations
,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
4 citations
,
November 2024 in “International Journal of Dermatology” This study examines the link between testosterone use and hair health in males, stressing the importance of developing guidelines for safe usage due to associated health risks like liver toxicity, gynecomastia, and hair loss.
March 2026 in “Canadian Urological Association Journal” This study observed that complementary and alternative medicine, often marketed to men as ways to enhance "optimization," "recovery," and "vitality," has become mainstream, with many believing in its benefits for testosterone, erections, libido, hair loss, and sperm quality.
January 2026 in “Frontiers in Nutrition” This study found that various dietary supplements positively impacted hair density and were well-tolerated among patients with androgenetic alopecia, suggesting they may be useful adjuncts or alternatives to standard treatments.
This study detailed a comprehensive hair therapy regimen for a 22-year-old male with androgenetic alopecia, observing significant improvements in scalp health and hair density over four months, though benefits regressed after stopping treatment, emphasizing the need for continuous adherence and multidisciplinary support.
July 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this animal study, methanolic extract of *Cordia plathytyrsa* increased testosterone synthesis in male rats but had limited effects on metabolic parameters, while *Piptadeniastrum africanum* raised triglycerides and both extracts did not cause oxidative stress.
38 citations
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May 2021 in “International Journal of Infectious Diseases” This study found that lower testosterone levels in male COVID-19 patients were associated with greater disease severity and longer hospital stays.
5 citations
,
May 2019 in “Hormone and Metabolic Research” This study reported that in embryo transfer cycles for women with nonclassic 21-hydroxylase deficiency, dexamethasone use was associated with improved pregnancy rates, and maintaining a BMI below 23.36 kg/m² increased pregnancy probabilities.
3 citations
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December 2024 in “Biomolecules & Therapeutics” This study found that Tanshinone I and Tanshinone IIA from Salviae Miltiorrhizae Radix inhibited Nox activity heightened by testosterone in a mouse model, reducing H₂O₂ production and cell apoptosis, and reversing testosterone-induced hair growth suppression, suggesting their potential as treatments for androgenetic alopecia.
3 citations
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June 2016 in “Gynecological Endocrinology” Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.
October 2023 in “FASEB bioAdvances” This study investigated the effects of Akkermansia muciniphila on testosterone-induced hair growth inhibition in mice, finding that both live and pasteurized forms significantly encouraged hair growth and increased hair follicle size and growth factor levels compared to testosterone treatment alone.
29 citations
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October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
17 citations
,
August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.
4 citations
,
July 2019 in “Children (Basel)” This review discusses recent findings on pathogenic mechanisms, diagnostic criteria, and treatment options for PCOS but reports no new clinical results.
3 citations
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July 2025 in “Reproductive Biology and Endocrinology” This study found that chromium, inositol, and Omega-3 are beneficial for improving lipid profiles in women with PCOS, and various supplements help alleviate other symptoms.
2 citations
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September 2020 This Mendelian randomization study reports that lifelong increased free testosterone in males was associated with improved bone mineral density and body composition but increased risks of prostate cancer, hypertension, and several other conditions.