A Rare Case of an Androgen-Producing Stromal Luteoma of the Ovary in a Postmenopausal Woman, Diagnosed by Selective Venous Blood Sampling

    June 2016 in “ Gynecological Endocrinology ”
    Dimitra Bogdanou, Gesine Meyer, Anja-Undine Stuecker, A. Thalhammer, Martin-Leo Hansmann, Joerg Bojunga
    Image of study
    TLDR Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.
    In 2016, a 55-year-old postmenopausal woman with severe virilization symptoms was diagnosed with a rare androgen-producing stromal luteoma of the ovary, a condition that was difficult to detect due to the tumor's small size. Conventional imaging methods such as CT, MRI, and ultrasound were unsuccessful in locating the tumor. Elevated serum testosterone levels suggested hyperandrogenism, but the exact source was identified only after selective venous catheterization and hormonal sampling (SVCHS) pinpointed significantly higher testosterone levels in the right ovarian vein. Following the diagnosis, a laparoscopic right oophrectomy was performed, leading to the regression of the patient's symptoms. The case study emphasizes the effectiveness of SVCHS as a diagnostic tool for localizing small hormone-producing ovarian tumors when other imaging techniques fail.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 1000+ results

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 1 month ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 2 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 2 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

    Related Research

    1 / 1 results