The Effectiveness of Nutritional Supplements in Improving Polycystic Ovary Syndrome in Women: A Systematic Review and Network Meta-Analysis

    July 2025 in “ Reproductive Biology and Endocrinology ”
    Ganggang Zhao, Yuxin Fan, Ruixia Li … Jianchang He
    Studysummary This study found that chromium, inositol, and Omega-3 are beneficial for improving lipid profiles in women with PCOS, and various supplements help alleviate other symptoms.
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    Research cited in this study 7

    1. Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome Frontiers in Endocrinology · 2019
    2. Effects of Melatonin Administration on Mental Health Parameters, Metabolic and Genetic Profiles in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial Journal of Affective Disorders · 2019
    3. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee The Journal of Clinical Endocrinology and Metabolism · 2019
    4. American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1 Endocrine Practice · 2015
    5. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    6. Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria The Lancet · 2007
    7. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome Fertility and Sterility · 2004