Curcumin
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Research
20 / 1000+ resultsresearch Novel Anti-Prostate Cancer Curcumin Analogues That Enhance Androgen Receptor Degradation Activity
This study found that new curcumin analogues, such as ASC-J9, can inhibit prostate cancer cell growth by promoting androgen receptor degradation.
research Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy
This study found that curcumin nanocrystals efficiently penetrated hair follicles down to the lower infundibulum in an ex-vivo pig ear model, regardless of the gel vehicle used, though passive dermal penetration varied with the vehicle’s skin hydrating properties.
research Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes in Photodynamic Therapy on Melanoma, Squamous Cell Carcinoma, and Normal Keratinocyte Cells
This study found that curcumin encapsulated in liposomes enhanced photodynamic therapy's effectiveness against skin cancer cells while reducing toxicity to normal human keratinocytes.
research Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness
This study reported that a newly formulated Curcumin-loaded proniosome, named F5, exhibited enhanced antiviral efficacy, stability, and safety when compared to Curcumin alone, and improved the therapeutic performance of Acyclovir by reducing its effective dose against Herpes simplex virus.
research Hair Follicle Targeting and Dermal Drug Delivery with Curcumin Drug Nanocrystals: Essential Influence of Excipients
This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.
research Effects of Curcumin on Glycemic Control and Lipid Profile in Polycystic Ovary Syndrome: Systematic Review with Meta-Analysis and Trial Sequential Analysis
This study found that curcumin may improve glycemic control and certain aspects of lipid metabolism in patients with polycystic ovary syndrome.
research Comparison of Two Encapsulated Curcumin Systems in Different Formulations for In Vitro Skin Penetration
In this study, curcumin was successfully encapsulated in ethyl cellulose and its blend with methyl cellulose, enhancing its skin penetration efficacy through o/w and w/o lotions compared to water suspensions.
research Curcumin-Based Nanoformulations Alleviate Wounds And Related Disorders: A Comprehensive Review
This study describes how incorporating curcumin-loaded nanoparticles into various nanoformulations can enhance its bioavailability and improve wound healing processes such as angiogenesis, collagen deposition, and cell proliferation.
research Fabrication and Characterization of Electrospun Membranes Based on Poly(ε-caprolactone), Poly(3-hydroxybutyrate) and Their Blend for Tunable Drug Delivery of Curcumin
This study found that electrospun poly(ε-caprolactone)/poly(3-hydroxybutyrate) blend fibers demonstrated nanometric dimensions and promising properties for drug delivery, with curcumin release linked to fiber morphology and processing parameters.
research Neurobehavioral Protective Properties of Curcumin Against Mercury Chloride Treated Mice Offspring
This study found that curcumin administration improved cognitive and anxiety-related behaviors and neurochemical levels in HgCl2 exposed mice pups, suggesting protective effects against heavy metal-induced neurotoxicity.
research Curcumin And Cancer Biology: Focusing Regulatory Effects In Different Signalling Pathways
This review describes how curcumin, a compound derived from turmeric, affects various cell signaling pathways involved in cancer progression, highlighting its potential as a therapeutic agent with fewer side effects compared to conventional cancer treatments.
research Hyaluronic Acid Micelles for Promoting the Skin Permeation and Deposition of Curcumin
CUR-loaded micelles improve skin delivery and effects of curcumin for pain and infections.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity
In this study, curcumin was efficiently loaded into PS–PAA nanoparticles at the formation stage, showing even distribution at low concentrations and good biocompatibility with human skin fibroblasts.
research Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3
This study evaluated curcumin analogues as potential inhibitors of 17β-HSD3 in rat and human models, but it does not report new clinical findings.
research Novel Chemically Modified Curcumin Analogs Exhibit Anti-Melanogenic Activity in Primary Human Melanocytes
This study demonstrated that novel curcumin analogs CMC2.24, CMC2.23, and CMC2.5 were more effective and less toxic than parent curcumin in inhibiting melanin production in normally pigmented human melanocytes, suggesting potential for skin depigmentation therapies.
research Skin Permeation of Curcumin Nanocrystals: Effect of Particle Size, Delivery Vehicles, and Permeation Enhancer
In this study using a porcine skin model, the researchers reported that smaller curcumin nanocrystals in xanthan gum gel showed higher passive skin penetration, while larger particles achieved deeper follicular accumulation.
research Anti-Androgenic Curcumin Analogues as Steroid 5-Alpha Reductase Inhibitors
This study found that certain curcumin analogs derived from natural plant sources exhibit anti-androgen activity by inhibiting steroid 5-alpha reductase, identifying key structural features for their potency and safety in treating androgen-related conditions.
research Particle Size Effect of Curcumin Nanocrystals on Transdermal and Transfollicular Penetration by Hyaluronic Acid-Dissolving Microneedle Delivery
This study found that smaller curcumin nanocrystals (60 nm) enhanced transdermal and transfollicular penetration more effectively than larger sizes, influenced by particle size.
research Curcumin/Fe-SiO2 Nano Composites with Multi-Synergistic Effects for Scar Inhibition and Hair Follicle Regeneration During Burn Wound Healing
This study found that Cur-Fe-mesoporous silica nanoparticles synergistically inhibited scar formation and promoted hair follicle regeneration in skin burn wound healing by releasing bioactive components like SiO32−, Fe3+, and Fe-Cur chelates.
research Validation of Replacement of the Synthetic Food Dye 'Sunset Yellow'-Induced Hepatotoxicity and Genotoxicity with the Nutraceutical 'Curcumin' in Mice
This study concluded that replacing the synthetic dye Sunset Yellow with curcumin as a colorant in foods may avoid cytotoxic and genotoxic effects observed in mice.