Efficacy of a Mixed Preparation Containing Piperine, Capsaicin, and Curcumin in the Treatment of Alopecia Areata

    March 2022 in “ Journal of cosmetic dermatology ”
    Yaqi Mao, Ziqian Xu, Jun Song, Yihui Xie, Xingyu Mei, Weimin Shi
    TLDR The mixed preparation helped hair regrowth but wasn't better than minoxidil.
    The study evaluated the efficacy and safety of a mixed preparation containing piperine, capsaicin, and curcumin in treating alopecia areata. Sixty patients were randomly divided into two groups: one treated with the mixed preparation twice daily and the other with 5% minoxidil once daily for 3 months. Both groups showed significant hair regrowth, with effective rates of 63.33% for the mixed preparation and 70% for minoxidil. The results indicated that while the mixed preparation is effective, it is not superior to minoxidil in short-term therapy. No serious adverse events were reported.
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