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    GlossaryPiperine

    alkaloid that gives black pepper its spiciness

    Piperine is an alkaloid responsible for the pungency of black pepper and long pepper. It enhances the bioavailability of various nutrients and drugs by inhibiting certain enzymes involved in their metabolism, making it a valuable compound in both culinary and medicinal contexts.

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      community My Research Compilation on Nutrafol

      in Research/Science  11 upvotes 2 years ago
      Nutrafol, a hair loss supplement, has limited and potentially biased research, with one study showing a 10% increase in hair count for women after 6 months but no significant results for men. The user concludes that cheaper, well-studied options like minoxidil may be more effective, especially for men, given the lack of evidence supporting Nutrafol.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 5 months ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community Going to try the theory posted here for the next 3-6 months

      in Treatment  188 upvotes 3 years ago
      User xEternex tries hair regrowth with daily broccoli sprouts, apple extract containing procyanidin b2, and microneedling. Others discuss potential issues with the experiment and share their experiences with vegetable consumption and hair growth.

      community Are there ever going to be any oral DHT blocking treatments in the future?

      in Product  6 upvotes 1 year ago
      The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2447 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.