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    Glossary PPAR-delta agonists

    compounds that activate receptors regulating metabolism and inflammation

    PPAR-delta agonists are compounds that activate the peroxisome proliferator-activated receptor delta (PPAR-δ), a type of nuclear receptor involved in regulating genes related to metabolism, inflammation, and cell differentiation. These agonists are being studied for their potential benefits in treating metabolic disorders, cardiovascular diseases, and certain types of hair loss, as they can influence fat burning, energy balance, and skin health.

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    1. Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics? Archives of dermatological research · 2015 · 60 citations
    2. PPAR-<i>γ</i> Agonists and Their Role in Primary Cicatricial Alopecia PPAR Research · 2017 · 38 citations
    3. Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth Acta dermato-venereologica · 2000 · 51 citations
    4. The Role of PPARβ/δ-Related Lipid Metabolism in High-Altitude Adaptation of Yak Coat Based on Proteomics and Metabolomics Cells · 2025
    5. Primary cicatricial alopecia: Recent advances in understanding and management The Journal of Dermatology · 2011 · 44 citations
    6. Peroxisome proliferator-activated receptors-mediated diabetic wound healing regulates endothelial cells’ mitochondrial function via sonic hedgehog signaling Burns & Trauma · 2025 · 5 citations
    7. Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications Medical Review · 2024 · 6 citations
    8. How to diagnose a lipodystrophy syndrome Annales d'Endocrinologie · 2012 · 53 citations
    9. Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin International journal of molecular sciences · 2021 · 9 citations
    10. The Impact of Glucagon-like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe? Biomolecules · 2025 · 4 citations
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