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    Glossary PPAR-delta agonists

    compounds that activate receptors regulating metabolism and inflammation

    PPAR-delta agonists are compounds that activate the peroxisome proliferator-activated receptor delta (PPAR-δ), a type of nuclear receptor involved in regulating genes related to metabolism, inflammation, and cell differentiation. These agonists are being studied for their potential benefits in treating metabolic disorders, cardiovascular diseases, and certain types of hair loss, as they can influence fat burning, energy balance, and skin health.

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    Research 30 of 988

    1. Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics? Archives of dermatological research · 2015 · 60 citations
    2. PPAR-<i>γ</i> Agonists and Their Role in Primary Cicatricial Alopecia PPAR Research · 2017 · 38 citations
    3. Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth Acta dermato-venereologica · 2000 · 51 citations
    4. The Role of PPARβ/δ-Related Lipid Metabolism in High-Altitude Adaptation of Yak Coat Based on Proteomics and Metabolomics Cells · 2025
    5. Primary cicatricial alopecia: Recent advances in understanding and management The Journal of Dermatology · 2011 · 44 citations
    6. Peroxisome proliferator-activated receptors-mediated diabetic wound healing regulates endothelial cells’ mitochondrial function via sonic hedgehog signaling Burns & Trauma · 2025 · 5 citations
    7. Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications Medical Review · 2024 · 6 citations
    8. How to diagnose a lipodystrophy syndrome Annales d'Endocrinologie · 2012 · 53 citations
    9. Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin International journal of molecular sciences · 2021 · 9 citations
    10. The Impact of Glucagon-like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe? Biomolecules · 2025 · 4 citations
    11. MEX3A regulates <i>Lgr5</i> <sup>+</sup> stem cell maintenance in the developing intestinal epithelium EMBO Reports · 2020 · 27 citations
    12. Relating neurosteroid modulation of inhibitory neurotransmission to behaviour Journal of Neuroendocrinology · 2021 · 18 citations
    13. Immunopathogenesis of Primary Cicatricial Alopecia Research Portal (King's College London) · 2013
    14. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    15. Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle Histochemistry and Cell Biology · 2021 · 13 citations
    16. Farmácia Lusitana, Vila do Conde e nos Serviços Farmacêuticos do Hospital CUF, Porto Open Repository of the University of Porto (University of Porto) · 2024
    17. Vitamin D, Lipid Metabolism and Prostate Cancer Trepo - Institutional Repository of Tampere University · 2009 · 1 citations
    18. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    19. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    20. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    21. Drug repositioning using <i>in silico</i> compound profiling Future Medicinal Chemistry · 2009 · 24 citations
    22. Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review) Molecular Medicine Reports · 2021 · 18 citations
    23. PCOS: update and diagnostic approach Clinical Biochemistry · 2018 · 16 citations
    24. Polycystic ovary syndrome: Pathophysiology, Symptoms, Risk factors, and Pharmacological treatment Research Journal for Social Affairs · 2024
    25. Efectos de la disminución de los depósitos tisulares de hierro sobre los factores de riesgo cardiovascular en pacientes con hiperandrogenismo ovárico funcional e_Buah · 2023
    26. Regulatory T cells in skin Immunology · 2017 · 110 citations
    27. Resveratrol derivatives: a patent review (2009 – 2012) Expert Opinion on Therapeutic Patents · 2013 · 28 citations
    28. Debatable Topics in PCOS Patients InTech eBooks · 2018 · 2 citations
    29. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    30. Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung Qucosa (Saxon State and University Library Dresden) · 2024