Myo-Inositol in Polycystic Ovary Syndrome: A Systematic Review and Positioning of Its Use

    March 2022 in “ International Journal of Nutrology ”
    Durval Ribas Filho, Carlos Alberto Nogueira‐de‐Almeida, Idiberto José Zotarelli Filho
    Image of study
    TLDR Myo-inositol improves fertility and metabolic health in PCOS with fewer side effects than metformin.
    This systematic review evaluated the effects of myo-inositol (MI) on women with Polycystic Ovary Syndrome (PCOS) across 16 randomized clinical trials. MI was found to improve fertility by increasing ovulation and fertilization rates, and it enhanced metabolic parameters related to insulin resistance, showing similar efficacy to metformin but with fewer side effects. It also improved pregnancy outcomes and reduced the risk of gestational diabetes. The review highlighted MI's role in insulin signaling and follicular development, noting its safety and effectiveness in improving ovulation and pregnancy rates. However, it emphasized the need for more extensive trials to confirm these findings. The Brazilian Association of Nutrology recommended MI for PCOS patients due to its clinical benefits and favorable safety profile.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 8 results

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  54 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Female androgenetic alopecia (w/ PCOS) starting treatment

      in Female  4 upvotes 9 months ago
      A female with PCOS and androgenetic alopecia is starting treatment with oral Minoxidil, topical Minoxidil 5% with finasteride, and plans to add mesotherapy. She previously tried anti-androgenic contraceptive pills but couldn't tolerate them and is using Myo Inositol for weight management.

      community Methionine? Glycine?

       6 upvotes 9 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community Have any of you used myoinositol

      in Research/Science  1 upvotes 2 years ago
      The conversation is about using inositol for hair loss, particularly its potential benefits for men, given its success in women with PCOS. The discussion includes treatments like Minoxidil, finasteride, and RU58841.

    Related Research

    3 / 3 results