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research MicroRNA control of signal transduction

1066 citations , March 2010 in “Nature Reviews Molecular Cell Biology”

This review discusses the potential regulation of signal transduction pathways by microRNAs in animal cells, aiming to identify biological processes that may be influenced by miRNA-mediated regulation, but it reports no new experimental outcomes.

research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

research Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice¹

519 citations , October 1998 in “Endocrinology”

The study found that normalizing mineral ion levels in vitamin D receptor-ablated mice prevented hyperparathyroidism and bone disorders but did not address hair loss, indicating the VDR's role in hair growth.

research Minoxidil: mechanisms of action on hair growth

397 citations , February 2004 in “British Journal of Dermatology”

This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.

research Mitochondrial dysfunction as a cause of ageing

384 citations , January 2008 in “Journal of Internal Medicine”

This review discusses the role of mitochondrial dysfunction in the ageing process and reports that its significance compared to other factors in mammalian ageing remains uncertain.

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Community Join

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community Miniaturization(?) after 12 months on oral fin/min compound

13 upvotes 1 month ago

After 12 months on an oral compound of finasteride, minoxidil, and biotin, the user experienced a seasonal shed and noticed thinner hairs at the hairline, raising concerns about ongoing miniaturization. Another user shared a similar experience and mentioned switching to dutasteride after genetic testing showed finasteride was ineffective.

community Started thinning at the crown and temples so i got this minoxidil, idk how to apply it because its spray

in Minoxidil 2 upvotes 4 months ago

The conversation discusses using minoxidil spray for hair thinning, with advice to use a dropper for better application. Many users recommend adding finasteride as a DHT blocker for more effective hair loss prevention.

community Are there actual risks with oral minoxidil? How can they be mitigated

in Minoxidil 20 upvotes 5 months ago

Oral minoxidil can cause side effects like heart issues, increased body hair, and facial puffiness, but these are often dose-dependent and temporary. Users report varying experiences, with some combining it with finasteride or RU58841 for better results, while others experience minimal or no side effects.

community Alguien más le pasa esto por el minoxidil?

in Minoxidil 1 upvotes 1 year ago

A 20-year-old male experienced mental fog after resuming topical minoxidil for hair loss, questioning if it's due to interactions with antidepressants. Suggestions included trying a lower concentration of minoxidil or alternatives like copper peptides.

community How Dangerous is Oral Min Really?

in Minoxidil 26 upvotes 1 year ago

Oral minoxidil is generally effective for hair loss but may cause side effects like heart palpitations and facial puffiness. Users highlight the importance of monitoring blood pressure due to potential cardiovascular risks.

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Learn

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learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.
Will I grow hair on my forehead? Myths and truths about minoxidil Minoxidil does not grow hair on the forehead due to low follicle density.
Minoxidil: the application and its effects counted in months Expect initial shedding in the first month, with visible results typically by three to six months.
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