Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the potential regulation of signal transduction pathways by microRNAs in animal cells, aiming to identify biological processes that may be influenced by miRNA-mediated regulation, but it reports no new experimental outcomes.

This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

The study found that normalizing mineral ion levels in vitamin D receptor-ablated mice prevented hyperparathyroidism and bone disorders but did not address hair loss, indicating the VDR's role in hair growth.

This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.

This review discusses the role of mitochondrial dysfunction in the ageing process and reports that its significance compared to other factors in mammalian ageing remains uncertain.

This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.

This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

This study found that disrupting the microtubule cytoskeleton in Arabidopsis root hairs caused loss of growth directionality and suggested microtubules interact with calcium gradients to regulate apical growth stability.

This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.

This study found that mitochondrial reactive oxygen species are crucial for normal epidermal differentiation and hair follicle growth, as demonstrated by impaired development in mice lacking these signals due to a keratinocyte-specific TFAM deficiency.

In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.

This study found that altering cell culture conditions to form three-dimensional papilla spheroids can restore the ability of human dermal papilla cells to induce hair growth in adult skin.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.

In this study, researchers found that mitochondrial complex I plays a crucial role in regulating innate immunity and bone remodeling, with Ndufs4 deletion causing systemic inflammation and osteopetrosis through various metabolic shifts and cellular mechanisms.

In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.

This study found that surgical deactivation of migraine headache trigger sites can significantly reduce migraine symptoms, with 92% of patients reporting at least a 50% reduction in migraine frequency, duration, or intensity.

This study found that removing PPARγ specifically from mouse adipose tissue led to severe fat loss, insulin resistance, diabetes, and associated metabolic abnormalities.

This study found that micro-niches within hair follicles create heterogeneity among stem cells and transit-amplifying cells, leading to specialized progenitors that control tissue morphogenesis and regeneration.

This study found that using a Picosecond IR Laser (PIRL) on mouse skin led to less tissue damage and scarring compared to conventional surgical lasers and tools.

This review discusses completed and ongoing clinical studies on microneedle-based technologies for cosmetic, therapeutic, and diagnostic applications and reports no new clinical results.

This guideline discusses evidence-based recommendations for managing acute migraine attacks and preventing migraines, highlighting effective treatments such as NSAIDs and triptans but reports no new clinical findings.

This article reviews the role of IGF-1 in acne pathogenesis and discusses how diet and smoking may influence insulin/IGF-1 signaling, but reports no new clinical results.

This study found that schizophrenia-derived neurons exhibited impaired differentiation and mitochondrial dysfunction, suggesting a potential link between these factors and neurodevelopmental processes in schizophrenia.

This study found that desmocollin 1 is crucial for strong adhesion and barrier maintenance in the mouse epidermis, with its absence leading to skin and hair issues resembling chronic dermatitis.

This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.

The researchers reported that hair follicle development and commensal microbe colonization promote the accumulation of regulatory T cells in neonatal skin, with the Ccl20-Ccr6 pathway playing a key role in this process.

In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.