The Effects of Probiotics, Prebiotics, and Synbiotics Supplementation on Polycystic Ovary Syndrome: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials

September 2022 in “ Research Square (Research Square) ”

Sepide Talebi, Sheida Zeraattalab-Motlagh, Nastaran Payandeh, Yahya Jalilpiran‬, Shakila Ansari, Hamed Mohammadi, Kurosh Djafarian, Mahsa Ranjbar, Sara Sadeghi, Mahdiyeh Taghizadeh, Sakineh Shab‐Bidar

probiotics prebiotics synbiotics polycystic ovary syndrome insulin resistance fasting glucose glycemic control lipid profile hormonal parameters PCOS

Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

Studysummary This study found that while pro-, pre-, and synbiotics may have beneficial effects on certain PCOS-related outcomes, the certainty of this evidence is low to very low.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

3 / 3 results

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This study found that androgenic alopecia is present in 22% of women with polycystic ovary syndrome and is associated with acne and hirsutism, but not with increased biochemical hyperandrogenemia or metabolic dysfunction beyond PCOS.

research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome

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This review discusses polycystic ovary syndrome, emphasizing its broad range of manifestations and associations with risks like type 2 diabetes and cardiovascular events, but reports no new clinical results.

research The Pathophysiology of Polycystic Ovary Syndrome

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This review discusses the complex etiology of polycystic ovary syndrome (PCOS), highlighting its association with insulin resistance and hyperandrogenism, but reports no clinical findings; the authors suggest further investigation of the pathophysiological mechanisms.