The Role of Probiotics and Synbiotics on Hirsutism

The review explored the potential role of probiotics and synbiotics in managing hirsutism, particularly in women with PCOS, by addressing insulin resistance (IR) and elevated androgen levels. Probiotics, such as Lactobacillus and Bifidobacterium, were shown to improve IR and reduce androgen levels, suggesting benefits for hirsutism management. A study with 60 women indicated that probiotic supplementation decreased testosterone levels and improved hormonal profiles. Synbiotics, combining probiotics and prebiotics, also reduced testosterone levels and improved insulin sensitivity. Despite promising findings, the review emphasized the need for further studies to understand the direct effects and optimal treatment regimens for hirsutism.