Efficacy and Safety of a Food Supplement Containing L-Cystine, Serenoa Repens Extract, and Biotin for Hair Loss in Healthy Males and Females: A Prospective, Randomized, Double-Blinded, Controlled Clinical Trial

    January 2017 in “ Journal of cosmetology & trichology ”
    Mridvika Narda, Sonia Aladren, Enza Cestone, Vincenzo Nobile
    Image of study
    TLDR The food supplement with L-cystine, Serenoa repens extract, and biotin safely reduced hair loss and improved hair growth in men and women.
    In 2017, a clinical trial with 70 participants evaluated the efficacy and safety of a food supplement containing L-cystine, Serenoa repens extract, and biotin for treating hair loss in healthy males and females. The study, which was a prospective, randomized, double-blinded, controlled trial, found that the supplement significantly reduced hair loss in women with acute telogen effluvium and improved the anagen/telogen ratio in men with androgenic alopecia, indicating more hair in the growing phase. Both men and women reported improvements in hair volume and appearance, and the treatment was well tolerated with only one reported adverse event. Despite its small sample size and the subjective nature of self-assessment questionnaires, the study concluded that the supplement was a safe and effective alternative to drug treatments for alopecia. The study was funded by Isdin SA, and the final content decisions were made by Dr. Vincenzo Nobile.
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results

    Related Community Posts Join

    6 / 407 results

      community Losing ground after 14 months of fin use and 11 months of min

      in Finasteride/Dutasteride  49 upvotes 2 years ago
      A 24-year-old person who is worried about their hair loss after 14 months of taking finasteride and 11 months of minoxidil. Replies to the post suggested sticking with their current regimen, that shedding from one part may not be telogen effluvium, and that shedding is normal with these drugs and they should evaluate in two to three months.

      community Dutasteride 0.5 mg - Oral Minoxidil 2.5 mg / First month

      in Progress Pictures  9 upvotes 1 year ago
      A 24-year-old male with androgenetic alopecia is using a treatment of Dutasteride 0.5 mg, oral Minoxidil 2.5 mg, L-cysteine, and a Ketoconazole/Caffeine/CBD shampoo. He's considering using a dermaroller to improve results, taking biotin and iron vitamins, and quitting nicotine due to its potential link to hair loss.

      community Fighting Hair loss AND Grey Hair

      in Treatment  18 upvotes 2 years ago
      The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

      community anything to add to my regime?

      in Advice 4 years ago
      The conversation is about a hair loss treatment regimen that includes finasteride, dutasteride, oral minoxidil, Dermapen, quercetin, N-acetyl L-cysteine, biotin, millet seed extract, MSM, OPC, green tea extract, high-dose vitamins B1-B12, boron, and silica. The user is seeking advice on additional treatments.

      community Methionine? Glycine?

       6 upvotes 8 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community Creating the Holy Grail Hair Loss Topical

       1 upvotes 4 years ago
      The conversation is about creating a natural hair loss topical using ingredients like cetirizine, Zinc Sulphate Heptahydrate, Safflower Extract, Ricinoleic Acid, and others. The user is seeking input and collaboration on this topical formula.

    Related Research

    1 / 1 results